6-Cyclopropyl-3-(4-methoxybenzyl)isoxazolo[5,4-b]pyridine-4-carboxylic acid CAS 1263215-62-8
| CAS No. | 1263215-62-8 |
| Molecular Formula | C18H16N2O4 |
| Molecular Weight | 324.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Cyclopropyl-3-(4-methoxybenzyl)isoxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 1263215-62-8), molecular formula C18H16N2O4 and molecular weight 324.33 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 6-Cyclopropyl-3-(4-methoxybenzyl)isoxazolo[5,4-b]pyridine-4-carboxylic acid (C18H16N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 324.33 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H16N2O4 |
| Molecular Weight | 324.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 2 |
Related Cyclopropyl Standards
- Methyl 6-cyclopropyl-3-(4-methoxyphenyl)isoxazolo[5,4-b]pyridine-4-carboxylate (CAS 1018125-63-7)
- 4-Cyclopropyl-n-[(4-fluorophenyl)methyl]-5-(3-methyl-1,2-oxazol-5-yl)pyrimidin-2-amine (CAS 1381549-86-5)
- 1-Cyclopropyl-3-(2-fluorophenyl)-1-(imidazo[1,2-a]pyridin-3-ylmethyl)urea (CAS 1448070-31-2)
- 9-Cyclopropyl-6,7-difluoro-8-methoxyisothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione (CAS 922491-07-4)
- N-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-sulfonamide (CAS 1416337-90-0)
- Ethyl 4-cyclopropyl-1-(2,6-dichlorophenyl)-1H-pyrazole-5-carboxylate (CAS 959631-18-6)
- 1-(2-Cyclopropyl-6-phenylpyrimidin-4-yl)piperidine-3-carboxylic acid (CAS 1707566-45-7)
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Recommended Standards
- Ethyl 4-hydroxy-7-methyl-2-oxo-1-phenyl-1,2-dihydro-1,8-naphthyridine-3-carboxylate (CAS 1253791-02-4)
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- (R)-3-Hydroxy Warfarin (CAS 124997-75-7)
- (S)-2-(((Benzyloxy)carbonyl)amino)-3-(4-cyanophenyl)propanoic acid (CAS 131669-07-3)
- (6-Chloro-[2,3'-bipyridin]-5-yl)methanol (CAS 1227584-64-6)
- 3-Amino-3-cyclobutylpropan-1-ol hydrochloride (CAS 2230802-42-1)
- Methyl 4-Amino-3-(trifluoromethyl)benzoate (CAS 167760-75-0)
- 2-Cyclopropyl-3-(1H-imidazol-1-yl)-2H-chromene-6-carboxylic acid (CAS 89781-98-6)
- 2-(Benzyloxy)-6-chloro-3-nitropyridine (CAS 353293-50-2)
- 2-Bromo-3-chloro-4-nitropyridine (CAS 1805138-23-1)
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- 2-Chloro-6-iodo-1-methyl-1H-benzo[d]imidazole (CAS 929193-27-1)
- 1-Benzyl-4,5-dihydro-1H-imidazole (CAS 61764-86-1)
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