4-Chloro-6-fluoro-2-(trifluoromethyl)quinoline-3-carbonitrile CAS 1263286-10-7
| CAS No. | 1263286-10-7 |
| Molecular Formula | C11H3ClF4N2 |
| Molecular Weight | 274.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 4-Chloro-6-fluoro-2-(trifluoromethyl)quinoline-3-carbonitrile (CAS 1263286-10-7), a certified reference material (molecular formula C11H3ClF4N2, MW 274.60 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 4-Chloro-6-fluoro-2-(trifluoromethyl)quinoline-3-carbonitrile is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 274.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H3ClF4N2 |
| Molecular Weight | 274.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-(4-Chloro-3,5-bis(difluoromethyl)-1H-pyrazol-1-yl)propanoic acid (CAS 1005678-67-0)
- Methyl 2-(4-chloro-3,5-bis(difluoromethyl)-1h-pyrazol-1-yl)acetate (CAS 1384856-22-7)
- 4-Chloro-8-fluoro-7-(trifluoromethyl)quinoline-3-carbonitrile (CAS 2188210-63-9)
- Ethyl 4-chloro-3,5-dinitrobenzoate (CAS 19649-81-1)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2,2-difluoro-N-methylethan-1-amine (CAS 1823184-35-5)
- 5-(2-Chloro-4-(trifluoromethyl)phenyl)furan-2-carbaldehyde (CAS 306936-04-9)
- 5-(2-Chloro-5-(trifluoromethyl)phenyl)furan-2-carbaldehyde (CAS 259196-40-2)
- 5-[4-Chloro-3-(trifluoromethyl)phenyl]-2-furaldehyde (CAS 58110-58-0)
Recommended Standards
- 3-(Chlorosulfonyl)-2,4,5-trifluorobenzoic acid (CAS 1242340-07-3)
- 3-(Chlorosulfonyl)-2,4,6-trifluorobenzoic acid (CAS 1242340-00-6)
- 5-(Chlorosulfonyl)-2,3,4-trifluorobenzoic acid (CAS 1242338-92-6)
- 2,4,7-trichloro-8-methoxy-pyrido[4,3-d]pyrimidine (CAS 2454491-03-1)
- 1-(3-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1542750-06-0)
- N-Boc-PEG5-alcohol (CAS 1404111-67-6)
- Cilazapril (CAS 88768-40-5)
- 3-Iodo-1H-indazole-7-carbaldehyde (CAS 944899-03-0)
- 6-Ethyl-2-((naphthalen-1-ylmethyl)thio)pyrimidin-4(3H)-one (CAS 899743-88-5)
- 3-Amino-3-(4-bromophenyl)cyclobutanol (CAS 1199556-66-5)
- 5-Amino-2-(2-(trifluoromethyl)phenyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1708169-01-0)
- 4-Methyl-2-(1-piperidinyl)-quinoline (CAS 5465-86-1)
- 1-Hydroxycycloheptane-1-carboxylic acid (CAS 20920-03-0)
- Tau Peptide (401-411)-Lys-Lys trifluoroacetate salt (CAS 2022956-59-6)
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