1-(3,4-Dichlorophenyl)-2-(1,3-dioxolan-2-yl)ethan-1-one CAS 1263365-49-6
| CAS No. | 1263365-49-6 |
| Molecular Formula | C11H10Cl2O3 |
| Molecular Weight | 261.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(3,4-Dichlorophenyl)-2-(1,3-dioxolan-2-yl)ethan-1-one is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(3,4-Dichlorophenyl)-2-(1,3-dioxolan-2-yl)ethan-1-one (CAS 1263365-49-6), molecular formula C11H10Cl2O3 and molecular weight 261.10 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-(3,4-Dichlorophenyl)-2-(1,3-dioxolan-2-yl)ethan-1-one (C11H10Cl2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 261.10 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(3,4-Dichlorophenyl)-2-(1,3-dioxolan-2-yl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10Cl2O3 |
| Molecular Weight | 261.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
Related Dichlorophenyl Standards
- Methyl 4-(3,5-dichlorophenyl)-4-oxobutanoate (CAS 1247776-11-9)
- 1-(2,5-Dichlorophenyl)-2-(1,3-dioxolan-2-yl)ethan-1-one (CAS 1263365-61-2)
- 1-(2,4-Dichlorophenyl)-2-(1,3-dioxolan-2-yl)ethan-1-one (CAS 1263365-99-6)
- 1-(2,3-Dichlorophenyl)-2-(1,3-dioxolan-2-yl)ethan-1-one (CAS 1263366-04-6)
- N-(3,4-dichlorophenyl)-3-hydroxyazetidine-1-carboxamide (CAS 1341781-04-1)
- 1-(2,6-Dichlorophenyl)-3-hydroxycyclobutane-1-carboxylic acid (CAS 1494015-98-3)
- 1-(2,4-Dichlorophenyl)-3-hydroxycyclobutane-1-carboxylic acid (CAS 1496480-06-8)
- Methyl 3-(2,4-dichlorophenyl)-3-methyloxirane-2-carboxylate (CAS 1499520-97-6)
Recommended Standards
- 3-bromo-4-cyanobenzene-1-sulfonamide (CAS 1261726-19-5)
- 4-bromo-3-cyanobenzene-1-sulfonamide (CAS 1261670-91-0)
- 1-(3,5-Dichloro-phenyl)-2-(1,3-dioxolan-2-yl)-ethanone (CAS 1263365-89-4)
- 4-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS 1256359-96-2)
- 6-(Aminomethyl)-4-(difluoromethyl)-3-nitropyridin-2-amine (CAS 1804684-99-8)
- 2-(2,4-Difluorobenzoyl)-6-methoxypyridine (CAS 1187165-31-6)
- 4-Methylmorpholin-3-one (CAS 20721-78-2)
- 2,4,4,5,7,7,8,10,10,11,13,13,14,16,16,17,17,18,18,18-ICosafluoro-2,5,8,11,14-pentakis(trifluoromethyl)-3,6,9,12,15-pentaoxaoctadecan-1-oic acid (CAS 52481-85-3)
- tert-Butyl (4-hydroxy-3-nitrophenyl)carbamate (CAS 197442-80-1)
- 1-(4-Aminopiperidin-1-yl)-3-cyclohexylpropan-1-one (CAS 1016534-65-8)
- 2,7-Dimethoxy-3,6-bis(methylthio)-naphthalene (CAS 105404-97-5)
- 4-(1,3-Dioxolan-2-yl)benzaldehyde (CAS 40681-88-7)
- 1-(Cyclobutylmethyl)-1H-1,2,3-triazole-4-carbaldehyde (CAS 1478465-26-7)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
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