4,4,4-Trifluorobutyric anhydride CAS 1263376-47-1
| CAS No. | 1263376-47-1 |
| Molecular Formula | C8H8F6O3 |
| Molecular Weight | 266.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4,4,4-Trifluorobutyric anhydride is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4,4,4-Trifluorobutyric anhydride (CAS 1263376-47-1), a certified reference material (molecular formula C8H8F6O3, MW 266.14 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 4,4,4-Trifluorobutyric anhydride is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 266.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4,4,4-Trifluorobutyric anhydride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8F6O3 |
| Molecular Weight | 266.14 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Recommended Standards
- 4-(3-Bromophenyl)-1,2-dimethyl-1H-imidazol-5-amine (CAS 1251115-00-0)
- 1-(5-Bromopyridin-3-yl)piperidine-4-carbonitrile (CAS 1289110-84-4)
- 3-(4-bromophenyl)-5-(propan-2-yl)-1H-1,2,4-triazole (CAS 1250511-16-0)
- n-((1h-Imidazol-2-yl)methyl)-3-bromo-4-methylaniline (CAS 1339473-72-1)
- (Z)-1,1,1-trifluoro-4-methoxypent-3-en-2-one (CAS 102145-82-4)
- 2-(Chloromethyl)-4-methylthiophene (CAS 1260667-87-5)
- [4-(piperidine-1-sulfonyl)phenyl]methanamine hydrochloride (CAS 1171923-10-6)
- Fluconazole Impurity 58 (CAS 123091-15-6 (free base))
- Phenyl (4-phenoxyphenyl)carbamate (CAS 860786-74-9)
- 5-(Trifluoromethyl)-4H-1,2,4-triazole-3-carbaldehyde (CAS 944906-25-6)
- 3-ethyl-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1012-95-9)
- 1-(6-Methylpyrazin-2-yl)piperidine-4-carbaldehyde (CAS 906352-82-7)
- Ethyl 4-cyano-1-(4-fluorophenyl)-1H-pyrazole-5-carboxylate (CAS 318497-87-9)
- Human IgE Pentapeptide HEPP (CAS 62087-72-3)
Why CATO?
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