Methyl 5-bromo-2-iodo-3-methylbenzoate CAS 1263376-81-3
| CAS No. | 1263376-81-3 |
| Molecular Formula | C9H8BrIO2 |
| Molecular Weight | 354.97 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 5-bromo-2-iodo-3-methylbenzoate (CAS 1263376-81-3), molecular formula C9H8BrIO2 and molecular weight 354.97 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 5-bromo-2-iodo-3-methylbenzoate (C9H8BrIO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine/iodine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 5-bromo-2-iodo-3-methylbenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8BrIO2 |
| Molecular Weight | 354.97 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br/I-containing |
Related Methyl Standards
- Methyl 4-bromo-2-iodo-6-methylbenzoate (CAS 1021344-69-3)
- Methyl 3-bromo-4-iodo-5-methylbenzoate (CAS 1160574-57-1)
- Methyl 2-(3-bromo-4-iodophenyl)acetate (CAS 1208075-30-2)
- Ethyl 2-bromo-5-iodobenzoate (CAS 1208075-44-8)
- Ethyl 2-bromo-3-iodobenzoate (CAS 1261442-65-2)
- Methyl 2-(2-bromo-5-iodophenyl)acetate (CAS 1261558-66-0)
- 4-Bromo-2-iodobenzoic acid ethyl ester (CAS 1261646-75-6)
- Ethyl 2-bromo-6-iodobenzoate (CAS 1261673-96-4)
Recommended Standards
- Methyl 2-(bromomethyl)-5-iodobenzoate (CAS 1310377-56-0)
- Methyl 3-bromo-5-iodo-2-methylbenzoate, 97% (CAS 1370600-52-4)
- Methyl 4-bromo-5-iodo-2-methylbenzoate (CAS 1370600-57-9)
- 5-Bromo-3-iodo-2-methylbenzoic acid methyl ester, 97% (CAS 1378861-84-7)
- 1-chloro-4-methyl-2,5-dinitrobenzene (CAS CATO-C3D-262915)
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