2-Bromo-3,6-difluorobenzoyl chloride CAS 1263377-04-3
| CAS No. | 1263377-04-3 |
| Molecular Formula | C7H2BrClF2O |
| Molecular Weight | 255.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Bromo-3,6-difluorobenzoyl chloride (C7H2BrClF2O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-Bromo-3,6-difluorobenzoyl chloride (CAS 1263377-04-3) is a high-purity analytical reference standard with the molecular formula C7H2BrClF2O and a molecular weight of 255.44 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Bromo-3,6-difluorobenzoyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H2BrClF2O |
| Molecular Weight | 255.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl/Br-containing |
Related Bromo Standards
- 2-Bromo-4,5-difluorobenzoyl chloride (CAS 103994-89-4)
- 6-Bromo-3-chloro-2,4-difluorobenzaldehyde (CAS 1160573-22-7)
- 3-Bromo-6-chloro-2,4-difluorobenzaldehyde (CAS 1160573-58-9)
- 4-Bromo-2,5-difluorobenzoyl chloride (CAS 123942-09-6)
- 5-Bromo-2,4-difluorobenzoyl chloride (CAS 1260654-60-1)
- 6-Bromo-2,3-difluorobenzoyl chloride (CAS 1263376-72-2)
- 3-Bromo-2,6-difluorobenzoyl chloride (CAS 1263376-89-1)
- 3-Bromo-2,4-difluorobenzoyl chloride (CAS 1507667-28-8)
Recommended Standards
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- 4-Dodecylmorpholine (CAS 1541-81-7)
- 4-Chloro-5-iodopyridin-2-ol (CAS 1628557-08-3)
- 2-Benzyl-1,2,3,4-tetrahydro-2,6-naphthyridine (CAS 345311-06-0)
- 2-Chloro-3-(dimethoxymethyl)-4-iodopyridine (CAS 1142192-28-6)
- N-(2-nitrobenzyl)oxetan-3-amine (CAS 1339909-51-1)
- 2-((Pyridin-4-ylmethyl)amino)cyclohexan-1-ol (CAS 1183728-40-6)
- 3-((2-(4-Chlorophenoxy)ethyl)thio)-N5,N7-diethyl-[1,2,4]triazolo[4,3-a][1,3,5]triazine-5,7-diamine (CAS 849124-92-1)
- 1-Bromo-2-chloro-3-[chloro-(difluoro)methoxy]benzene (CAS 1417568-86-5)
- 2,2,6,6-Tetramethyl-1-(1-phenylethoxy)piperidine (CAS 154554-67-3)
- 2-Chloro-4-cyclopentylpyridine (CAS 1209457-89-5)
- 57625-08-8 (2-Azatricyclo[3.3.1.1~3,7~]decan-2-yl)oxidanyl DTXSID80655315 (CAS 57625-08-8)
- Acetyl Hexapeptide-39 (CAS 1382088-38-1)
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