4-Bromo-nicotinic acid methyl ester hydrobromide CAS 1263378-22-8
| CAS No. | 1263378-22-8 |
| Molecular Formula | C7H6BrNO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Bromo-nicotinic acid methyl ester hydrobromide (CAS 1263378-22-8), molecular formula C7H6BrNO2HBr and molecular weight 296.95 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-Bromo-nicotinic acid methyl ester hydrobromide (C7H6BrNO2HBr) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 296.95 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Bromo-nicotinic acid methyl ester hydrobromide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6BrNO2 HBr |
| Molecular Weight | 296.95 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
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- 14-Bromo-1-tetradecyne (CAS 1000014-24-3)
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Recommended Standards
- Benzyl 2-acetamido-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-2-deoxy-a-D-glucopyranoside (CAS 67313-30-8)
- 1-methyl-1H-pyrrolo[2,3-b]pyridine-2-carbaldehyde (CAS 1368111-06-1)
- Stiripentol Impurity 3 (CAS 106174-98-5)
- Trans-2-(4-methylcyclohexyl)isopropanol (CAS 5114-00-1)
- 5-(2,4-dimethylphenyl)-4H-1,2,4-triazol-3-amine (CAS 502685-90-7)
- 2-Bromo-6-chlorodibenzo[b,d]furan (CAS 2138490-84-1)
- 3-Bromo-5-(tert-butyl)benzo[b]thiophene (CAS 1780644-81-6)
- 1-Benzyl-3-(4-tert-butylphenyl)-3-[(2,4-dimethoxyphenyl)methyl]thiourea (CAS 306730-47-2)
- 5-Methylisothiazole-3-carbonitrile (CAS 65735-08-2)
- Semaglutide impurity 49 (CAS CATO-C4X-222649)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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