(R)-1-(4-Chlorobenzyl)pyrrolidin-3-ol CAS 1264036-65-8
| CAS No. | 1264036-65-8 |
| Molecular Formula | C11H14ClNO |
| Molecular Weight | 211.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(R)-1-(4-Chlorobenzyl)pyrrolidin-3-ol (CAS 1264036-65-8) is a high-purity analytical reference standard with the molecular formula C11H14ClNO and a molecular weight of 211.69 g/mol.
The molecular framework of (R)-1-(4-Chlorobenzyl)pyrrolidin-3-ol (C11H14ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), (R)-1-(4-Chlorobenzyl)pyrrolidin-3-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H14ClNO |
| Molecular Weight | 211.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- 1-(2-Chlorobenzyl)pyrrolidin-3-ol, 95% (CAS 1033012-63-3)
- 1-(3-Chlorobenzyl)pyrrolidin-3-ol (CAS 1033012-64-4)
- (S)-1-(4-Chlorobenzyl)pyrrolidin-3-ol (CAS 1261233-81-1)
- (S)-1-(2-Chlorobenzyl)pyrrolidin-3-ol (CAS 1261235-20-4)
- (R)-1-(2-Chlorobenzyl)pyrrolidin-3-ol (CAS 1264036-08-9)
- (R)-1-(3-chlorobenzyl)pyrrolidin-3-ol (CAS 1314355-33-3)
- N-(2-chlorobenzyl)tetrahydrofuran-3-amine (CAS 1339502-83-8)
- 3-(3-Chlorobenzyl)pyrrolidin-3-ol (CAS 1339565-99-9)
Recommended Standards
- (S)-1-(3-Chloro-benzyl)-pyrrolidin-3-ol (CAS 1264038-70-1)
- 3-(3-Chloro-4-methoxybenzyl)azetidine (CAS 1268103-44-1)
- (S)-1-(3-chloro-4-methoxyphenyl)but-3-en-1-amine (CAS 1269802-21-2)
- 3-(3-Chloro-4-methoxyphenyl)pyrrolidine (CAS 1260867-97-7)
- (2-Methylallyl)amine hydrochloride 2-methylprop-2-en-1-amine hydrochloride 28148-54-1 (CAS 28148-54-1)
- 1-Methoxy-4-(2,2,2-trifluoroethyl)benzene (CAS 157928-44-4)
- (2-Methylpyrimidin-5-yl)-acetonitrile (CAS 1581684-23-2)
- (3-Bromophenyl)(phenyl)sulfane (CAS 52089-10-8)
- (3S,6S)-3-Benzyl-6-isopropylpiperazine-2,5-dione (CAS 35590-86-4)
- Triphenyl(p-tolyl)phosphonium iodide (CAS 10111-23-6)
- Calcitriol Impurity 30 (CAS 69389-87-3)
- 3-(3,4-Dihydro-2h-1-benzopyran-6-yl)propanoic acid (CAS 889939-53-1)
- Ethyl 4-(4-chlorophenyl)-2-(3-chloropropanamido)thiophene-3-carboxylate (CAS 457621-59-9)
- Pancreatic Polypeptide (bovine) (CAS 179986-89-1)
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