4-Bromoquinazolin-2-amine CAS 1264037-59-3
| CAS No. | 1264037-59-3 |
| Molecular Formula | C8H6BrN3 |
| Molecular Weight | 224.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Bromoquinazolin-2-amine.
4-Bromoquinazolin-2-amine (CAS 1264037-59-3) is a high-purity analytical reference standard with the molecular formula C8H6BrN3 and a molecular weight of 224.06 g/mol.
Structurally, 4-Bromoquinazolin-2-amine (C8H6BrN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 224.06 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6BrN3 |
| Molecular Weight | 224.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Bromoquinazolin Standards
- 5-Bromoquinazolin-4-amine (CAS 1201784-87-3)
- 8-Bromoquinazolin-4-amine (CAS 1260657-19-9)
- 6-Bromoquinazolin-4-amine (CAS 21419-48-7)
- 2-Bromoquinazolin-6-ol (CAS 1289192-16-0)
- 5-Bromoquinazolin-4-ol (CAS 147006-47-1)
- 7-Bromoquinazolin-4(3H)-one (CAS 194851-16-6)
- 2-Bromoquinazolin-4(3H)-one (CAS 872998-62-4)
- 2-Bromoquinazolin-8-ol (CAS 953040-40-9)
Recommended Standards
- 2-Bomoquinazolin-4-amine (CAS 1264036-99-8)
- (4S,5S)-4,5-bis(trifluoromethyl)-1,3-dioxolan-2-one (CAS 127213-78-9)
- 4-(5-Bromo-1H-imidazol-2-yl)pyridine (CAS 1260682-35-6)
- 2-Bromo-5-(1h-pyrazol-1-yl)pyridine (CAS 1314355-12-8)
- (S)-3-(2-(methylamino)propyl)phenol (CAS 339986-99-1)
- Tetra(p-bromophenyl)porphyrin (CAS 29162-73-0)
- 2-Amino-3-Bromo-7-Fluoro-9H-Fluoren-9-Ol (CAS 1960-60-7)
- 4-Chloro-3-formyl-1H-indazole-6-carboxylic Acid (CAS 885523-22-8)
- 2-Methoxy-5-(5-(trifluoromethyl)-1H-tetrazol-1-yl)benzaldehyde (CAS 168267-11-6)
- 5-Methoxy-1-(trifluoromethyl)-1-indanol (CAS 188726-17-2)
- (S)-4-methyl-3-(methylamino)pentanoic acid (CAS 1628734-62-2)
- Methyl 3-(furan-2-carboxamido)-4-(phenylsulfonyl)benzoate (CAS 439096-84-1)
- 2-(5-Fluoro-1-benzothiophen-3-yl)ethan-1-amine (CAS 767617-20-9)
- D-Tyr10-Tirzepatide (CAS CATO-CPTD788922)
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