1-(5-Chloro-2-methylphenyl)-3-(ethoxycarbonyl)-4,5-dihydro-1h-pyrazole-5-carboxylic acid CAS 1264041-75-9
| CAS No. | 1264041-75-9 |
| Molecular Formula | C14H15ClN2O4 |
| Molecular Weight | 310.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(5-Chloro-2-methylphenyl)-3-(ethoxycarbonyl)-4,5-dihydro-1h-pyrazole-5-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(5-Chloro-2-methylphenyl)-3-(ethoxycarbonyl)-4,5-dihydro-1h-pyrazole-5-carboxylic acid (CAS 1264041-75-9), molecular formula C14H15ClN2O4 and molecular weight 310.73 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(5-Chloro-2-methylphenyl)-3-(ethoxycarbonyl)-4,5-dihydro-1h-pyrazole-5-carboxylic acid (C14H15ClN2O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(5-Chloro-2-methylphenyl)-3-(ethoxycarbonyl)-4,5-dihydro-1h-pyrazole-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H15ClN2O4 |
| Molecular Weight | 310.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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- 2-Chloro-4-fluoro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1227270-84-9)
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- 2-((4-Butyl-6-chloro-2-oxo-2h-chromen-7-yl)oxy)acetic acid (CAS 843619-85-2)
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- 3-Chloro-4-fluoro-N-(5-methylisoxazol-3-yl)benzo[b]thiophene-2-carboxamide (CAS 588675-34-7)
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Recommended Standards
- Methyl 6-(chloromethyl)-4-(4-methoxyphenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 1260904-42-4)
- 1-(3-Chlorophenyl)-3-(ethoxycarbonyl)-5-methyl-4,5-dihydro-1h-pyrazole-5-carboxylic acid (CAS 1264044-19-0)
- (R)-4-(4-(5-(chloromethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one (CAS 1252018-28-2)
- 1-(2-Chlorophenyl)-3-(ethoxycarbonyl)-5-methyl-4,5-dihydro-1h-pyrazole-5-carboxylic acid (CAS 1264046-73-2)
- 2-(Pyrrolidin-1-yl)-5-(4H-1,2,4-triazol-4-yl)benzonitrile (CAS 1269354-97-3)
- 2-Amino-N-(3-chloro-4-methoxyphenyl)benzamide (CAS 571150-53-3)
- Ethyl 4-(1H-indol-3-yl)-4-oxobutanoate (CAS 21859-98-3)
- N-acetyl-N-hydroxy-2-phenylacetamide (CAS 77130-75-7)
- 1-Allyl-4,6-dimethoxy-1H-indole-2-carboxylic acid (CAS 1361003-97-5)
- 2-(4-(Difluoromethyl)-5-hydroxy-3-(trifluoromethyl)pyridin-2-yl)acetonitrile (CAS 1806985-56-7)
- 4-(4-Methylpiperazin-1-yl)-5,6,7,8-tetrahydro-1,5-naphthyridine-2-carbonitrile (CAS 1263209-49-9)
- SR 9011 (CAS 1379686-29-9)
- 3,4-Difluoro-2,6-diiodophenol (CAS 1228093-47-7)
- Semaglutide Impurity 139 (CAS CATO-C4X-2226139)
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