6-Methoxyquinazoline-2-carbaldehyde CAS 1266119-42-9
| CAS No. | 1266119-42-9 |
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
6-Methoxyquinazoline-2-carbaldehyde (CAS 1266119-42-9), molecular formula C10H8N2O2 and molecular weight 188.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Methoxyquinazoline-2-carbaldehyde (C10H8N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 2 |
Related Methoxyquinazoline Standards
- 4-Methoxyquinazoline-6-carbaldehyde (CAS 648449-03-0)
- 6-Methoxyquinazoline-5,8-dione (CAS 87039-50-7)
- 7-Methoxyquinazoline-4,6-diamine (CAS 1363151-64-7)
- 6-Methoxyquinazoline-2,4-diamine (CAS 141400-11-5)
- 5-Methoxyquinazoline-2,4-diamine (CAS 27018-21-9)
- 4-Methoxyquinazoline-5-carbonitrile (CAS 1231761-60-6)
- 4-Methoxyquinazoline-6-carbonitrile (CAS 1823343-70-9)
- 4-Methoxyquinazoline-6,7-diol (CAS 1312937-40-8)
Recommended Standards
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