Methyl 5-bromo-3-(2,2,2-trichloroacetamido)thiophene-2-carboxylate CAS 1266189-95-0
| CAS No. | 1266189-95-0 |
| Molecular Formula | C8H5BrCl3NO3S |
| Molecular Weight | 381.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 381.46 g/mol gives Methyl 5-bromo-3-(2,2,2-trichloroacetamido)thiophene-2-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 5-bromo-3-(2,2,2-trichloroacetamido)thiophene-2-carboxylate (CAS 1266189-95-0), molecular formula C8H5BrCl3NO3S and molecular weight 381.46 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Methyl 5-bromo-3-(2,2,2-trichloroacetamido)thiophene-2-carboxylate (C8H5BrCl3NO3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 381.46 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 5-bromo-3-(2,2,2-trichloroacetamido)thiophene-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5BrCl3NO3S |
| Molecular Weight | 381.46 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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