2-(4-Hydroxythiazol-2-yl)acetonitrile CAS 126743-35-9
| CAS No. | 126743-35-9 |
| Molecular Formula | C5H4N2OS |
| Molecular Weight | 140.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(4-Hydroxythiazol-2-yl)acetonitrile (CAS 126743-35-9), molecular formula C5H4N2OS and molecular weight 140.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(4-Hydroxythiazol-2-yl)acetonitrile (C5H4N2OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 2-(4-Hydroxythiazol-2-yl)acetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H4N2OS |
| Molecular Weight | 140.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Hydroxythiazol Standards
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Recommended Standards
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Why CATO?
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