| CAS No. | 1268367-99-2 |
| Molecular Formula | C16H10S2 |
| Molecular Weight | 266.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 266.38 g/mol gives Brexpiprazole Impurity 133 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Brexpiprazole Impurity 133 (CAS 1268367-99-2), a pharmacopoeial impurity reference standard (molecular formula C16H10S2, MW 266.38 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to sulfur-containing functionality, a polycyclic aromatic system, Brexpiprazole Impurity 133 is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 266.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
| Molecular Formula | C16H10S2 |
| Molecular Weight | 266.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Sulfur Atoms | 2 |