4-Fluoro-3-(methanesulfonyl)phenylboronic acid CAS 1268496-35-0
| CAS No. | 1268496-35-0 |
| Molecular Formula | C7H8BFO4S |
| Molecular Weight | 218.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Fluoro-3-(methanesulfonyl)phenylboronic acid (CAS 1268496-35-0), a certified reference material (molecular formula C7H8BFO4S, MW 218.01 g/mol) for analytical method development and quality control.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 4-Fluoro-3-(methanesulfonyl)phenylboronic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 218.01 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8BFO4S |
| Molecular Weight | 218.01 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Fluoro Standards
- (2-Fluoro-5-(methylsulfonyl)phenyl)boronic acid (CAS 1313617-71-8)
- 4-Fluoro-2-(methylsulfonyl)phenylboronic acid (CAS 1402238-31-6)
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- 2-Fluoro-4-(methylsulfonyl)phenylboronic Acid (CAS 957060-85-4)
- 3-Fluoro-4-(methylsulfonyl)phenylboronic Acid (CAS 648904-83-0)
- 5-Fluoro-4-trifluoromethyl-indan-1-one (CAS 1202577-94-3)
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Recommended Standards
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- 3-((5-Chloropyridin-2-yl)amino)propanoic acid (CAS 33390-63-5)
- 2-Fluoro-4,5-dimethylbenzoic acid (CAS 1427427-79-9)
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- 1H-Pyrrolo[3,2-b]pyridine-2,5(3H,4H)-dione (CAS 1190311-76-2)
- Tert-butyl (1-(1,3-dioxoisoindolin-2-yl)-3-phenylpropan-2-yl)carbamate (CAS 885266-56-8)
- 2,6-Diaminopyrimidin-4(5H)-one (CAS 26279-64-1)
- 2-(2,6-Dichlorophenyl)-3-oxobutanenitrile (CAS 186196-04-3)
- 5-(((3R,4S)-4-Ethyl-5-oxotetrahydrofuran-3-yl)methyl)-1-hexyl-1-methyl-1H-imidazol-1-ium iodide (CAS 63868-84-8)
- 6-Fluoro-7-nitroquinoxalin-2(1H)-one (CAS 934690-32-1)
- Neuropeptide AF (human) (CAS 192387-38-5)
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