4-Hydroxy-6-methyl-2-(trifluoromethyl)quinoline-3-carboxylic acid CAS 126855-84-3
| CAS No. | 126855-84-3 |
| Molecular Formula | C12H8F3NO3 |
| Molecular Weight | 271.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 4-Hydroxy-6-methyl-2-(trifluoromethyl)quinoline-3-carboxylic acid (CAS 126855-84-3), a certified reference material (molecular formula C12H8F3NO3, MW 271.19 g/mol) for analytical method development and quality control.
4-Hydroxy-6-methyl-2-(trifluoromethyl)quinoline-3-carboxylic acid (C12H8F3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4-Hydroxy-6-methyl-2-(trifluoromethyl)quinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8F3NO3 |
| Molecular Weight | 271.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- Methyl 4-hydroxy-8-(trifluoromethyl)quinoline-2-carboxylate (CAS 1065074-52-3)
- Methyl 4-hydroxy-7-(trifluoromethyl)quinoline-2-carboxylate (CAS 1072944-69-4)
- Methyl 4-hydroxy-6-(trifluoromethyl)quinoline-2-carboxylate (CAS 123158-31-6)
- Methyl 4-hydroxy-6-(trifluoromethyl)quinoline-2-carboxylate (CAS 1422284-64-7)
- Methyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate (CAS 1448259-54-8)
- Methyl 4-hydroxy-8-(trifluoromethyl)quinoline-3-carboxylate (CAS 1820673-41-3)
- 4-Hydroxy-2-methyl-8-(trifluoromethyl)quinoline-3-carboxylic acid (CAS 64321-67-1)
- Ethyl 4-hydroxy-2-(trifluoromethyl)quinoline-3-carboxylate (CAS 75999-59-6)
Recommended Standards
- 1-(2-Bromo-1-isobutoxyethyl)-4-methylbenzene (CAS 1250272-51-5)
- 4-(2,2,2-trifluoroethoxy)quinoline-2-carboxylic acid (CAS 1281584-65-3)
- 1-(2-Bromo-1-(tert-butoxy)ethyl)-3-methylbenzene (CAS 1250172-40-7)
- 1-((5-Bromopentyl)oxy)-3-ethylbenzene (CAS 1340143-85-2)
- 2-Chloro-4-methoxy-3-methylbenzoic acid (CAS 196819-88-2)
- 4-chloro-1-[(4-methylphenoxy)methyl]-1H-pyrazole-3-carboxylic acid (CAS 1006444-40-1)
- (2-(2-Morpholinoethoxy)phenyl)methanamine (CAS 540753-13-7)
- Methyl 2-(Bromomethyl)-4-methoxybenzoate (CAS 15365-25-0)
- 2-(2-(Adamantan-1-yl)ethoxy)acetic acid (CAS 924843-94-7)
- 2-(Dimethylamino)-2-(hydroxymethyl)propane-1,3-diol (CAS 1112-24-9)
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