N,N-dimethyl-1-(4-(piperidin-2-yl)phenyl)methanamine dihydrochloride CAS 1269052-75-6
| CAS No. | 1269052-75-6 |
| Molecular Formula | C14H22N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
N,N-dimethyl-1-(4-(piperidin-2-yl)phenyl)methanamine dihydrochloride (CAS 1269052-75-6), molecular formula C14H22N2HCl and molecular weight 254.80 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N,N-dimethyl-1-(4-(piperidin-2-yl)phenyl)methanamine dihydrochloride (C14H22N2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H22N2 2*HCl |
| Molecular Weight | 254.80 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- (2-Phenoxyethyl)(p-tolyl)sulfane (CAS 94001-61-3)
- dimethyl pimelate (CAS 1732-08-7)
- 2-((1E,3R,4S,5E)-3,4-Dihydroxyhepta-1,5-dien-1-yl)-6-hydroxybenzaldehyde (CAS 24868-59-5)
- Lifitegrast Impurity 62 (CAS CATO-C4X-240962)
- 4,5-Dimethoxy-2-(piperidine-1-carbonyl)aniline (CAS 916164-73-3)
- 2-Acetoxy-3,4,5-trifluorobenzophenone (CAS 890099-18-0)
- 2-Methoxy-5-nitropyridin-3-ol (CAS 138256-03-8)
- Z-Gly-ol (CAS 77987-49-6)
- 5-(4-Methylphenyl)-2-(piperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine-7-carboxylic acid (CAS 852400-01-2)
- Semaglutide impurity 69 (CAS CATO-C4X-222669)
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