2-(Pyridin-3-yl)thiazol-5-amine hydrochloride CAS 1269054-63-8
| CAS No. | 1269054-63-8 |
| Molecular Formula | C8H7N3S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 213.68 g/mol gives 2-(Pyridin-3-yl)thiazol-5-amine hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(Pyridin-3-yl)thiazol-5-amine hydrochloride (CAS 1269054-63-8), molecular formula C8H7N3SHCl and molecular weight 213.68 g/mol, is a CATO reference standard with documented purity and traceability.
2-(Pyridin-3-yl)thiazol-5-amine hydrochloride (C8H7N3SHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7N3S HCl |
| Molecular Weight | 213.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Pyridin Standards
- 3-[(E)-2-(Pyridin-3-yl)ethenyl]-1,2-dihydroquinoxalin-2-one (CAS 1000169-10-7)
- 2-(pyridin-2-ylsulfanyl)acetic acid (CAS 10002-29-6)
- 4-(Pyridin-3-yloxy)benzenesulfonic acid (CAS 1000340-09-9)
- 2-(2-Oxo-2-(pyridin-4-yl)ethylidene)thiazolidin-4-one (CAS 1000932-15-9)
- 2-[2-oxo-2-(pyridin-3-yl)ethylidene]-1,3-thiazolidin-4-one (CAS 1000932-62-6)
- N-(pyridin-3-ylmethyl)sulfamide (CAS 1000933-31-2)
- Ethyl 1-(2-pyridin-2-ylethyl)piperidine-4-carboxylate (CAS 1000941-29-6)
- 1-Methyl-4-(pyridin-2-ylmethyl)piperazine (CAS 100158-57-4)
Recommended Standards
- 5-Bromo-4,5-dihydrooxazolo[5,4,3-ij]quinoline-2,6-dione (CAS 75655-13-9)
- 5-Chloro-2-pyridylacetonitrile (CAS 185315-51-9)
- 3-[4-(Dimethylamino)phenyl]-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazol-3-yl]acrylonitrile (CAS 303996-79-4)
- N-(3-Amino-4-fluorophenyl)-2-(3-fluorophenoxy)-acetamide (CAS 954263-27-5)
- 2-(Benzo[d][1,3]dioxol-5-yl)benzoicacid (CAS 24351-54-0)
- 3-(2-Hydroxyethyl)piperazine-2,5-dione (CAS 101080-13-1)
- (2-Bromophenyl)(methyl)selane (CAS 14403-31-7)
- Methyl 8-Boc-8-azabicyclo[3.2.1]octane-2-carboxylate (CAS 1033820-28-8)
- 1-((Tetrahydro-2h-pyran-2-yl)methyl)-1h-pyrazol-3-amine (CAS 1182917-73-2)
- Peptide Impurity 24 (CAS CATO-CPTD788824)
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