2-(3-methylphenyl)-1,3-thiazole-4-sulfonyl chloride CAS 1269152-70-6
| CAS No. | 1269152-70-6 |
| Molecular Formula | C10H8ClNO2S2 |
| Molecular Weight | 273.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(3-methylphenyl)-1,3-thiazole-4-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-(3-methylphenyl)-1,3-thiazole-4-sulfonyl chloride (CAS 1269152-70-6) is a high-purity analytical reference standard with the molecular formula C10H8ClNO2S2 and a molecular weight of 273.76 g/mol.
The molecular framework of 2-(3-methylphenyl)-1,3-thiazole-4-sulfonyl chloride (C10H8ClNO2S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H8ClNO2S2 |
| Molecular Weight | 273.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related methylphenyl Standards
- 4-(4-Methylphenyl)-5-(thiophen-2-yl)-4h-1,2,4-triazole-3-thiol (CAS 496787-40-7)
- (S)-1-[(4-Methylphenyl)sulfonyl]-2-phenylaziridine (CAS 149769-84-6)
- (R)-1-[(4-Methylphenyl)sulfonyl]-2-phenylaziridine (CAS 62596-62-7)
- 4-[(4-methylphenyl)sulfanyl]-3-nitrobenzaldehyde (CAS 270262-89-0)
- Ethyl 4-([(4-methylphenyl)amino]carbonyl)-1h-imidazole-5-carboxylate (CAS 313519-82-3)
- 4-Methylphenyl 5-nitropyridin-2-ylcarbamate (CAS 1989954-39-3)
- (3Z)-3-[(3-Methylphenyl)imino]-1-(prop-2-yn-1-yl)-2,3-dihydro-1H-indol-2-one (CAS 477886-41-2)
- 3-(3-Methylphenyl)-2-sulfanylidene-1H,2H,3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 1154244-40-2)
Recommended Standards
- 4-(4-methyl-1,3-thiazol-2-yl)benzene-1-sulfonyl chloride (CAS 1247607-26-6)
- 3-(4-methyl-1,3-thiazol-2-yl)benzene-1-sulfonyl chloride (CAS 1342075-96-0)
- 8'-Chloro-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline] (CAS 1243103-30-1)
- 2-methyl-5-phenyl-1,3-thiazole-4-sulfonyl chloride (CAS 1394042-25-1)
- 5-((2H-Tetrazol-5-yl)methyl)-3-methyl-3,5-dihydro-4H-imidazo[4,5-d]pyridazin-4-one (CAS 2639697-40-6)
- N,N-Diethyl-1,3-benzenediamine Hydrochloride (CAS 214707-03-6)
- rac Clopidogrel-d8 Hydrogen Sulfate (Major) (CAS 1346598-07-9)
- (6-Chloropyridin-3-yl)thiourea (CAS 125117-97-7)
- 2-Bromo-1H-pyrrolo[2,3-b]pyridine (CAS 1083181-25-2)
- 2-[4-(aminomethyl)piperidin-1-yl]-N,N-dimethylacetamide dihydrochloride (CAS 1803603-45-3)
- N-(3-(6-(dimethylamino)-4-(trifluoromethyl)pyridin-2-yl)benzyl)-N-methylglycine (CAS 1311279-02-3)
- 1H-pyrrole-3-carbonitrile, 2-amino-4-methyl-1-propyl- (CAS 804519-27-5)
- 1-(4-Bromophenyl)-1H-imidazole (CAS 10040-96-7)
- (Asp28)-Exenatide trifluoroacetate salt (CAS 1678417-24-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com