2-(1-(2-Fluorophenyl)-1H-pyrazol-5-yl)pyridine CAS 1269291-78-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1269291-78-2
Molecular FormulaC14H10FN3
Molecular Weight239.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(1-(2-Fluorophenyl)-1H-pyrazol-5-yl)pyridine CAS 1269291-78-2 chemical structure

Description

The occurrence of 2-(1-(2-Fluorophenyl)-1H-pyrazol-5-yl)pyridine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-(1-(2-Fluorophenyl)-1H-pyrazol-5-yl)pyridine (CAS 1269291-78-2) is a high-purity analytical reference standard with the molecular formula C14H10FN3 and a molecular weight of 239.25 g/mol.

The molecular framework of 2-(1-(2-Fluorophenyl)-1H-pyrazol-5-yl)pyridine (C14H10FN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H10FN3
Molecular Weight239.25 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms3

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