4-bromo-6-fluoronicotinic acid CAS 1269293-70-0
| CAS No. | 1269293-70-0 |
| Molecular Formula | C6H3BrFNO2 |
| Molecular Weight | 220.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-bromo-6-fluoronicotinic acid.
4-bromo-6-fluoronicotinic acid (CAS 1269293-70-0) is a high-purity analytical reference standard with the molecular formula C6H3BrFNO2 and a molecular weight of 220.00 g/mol.
The molecular framework of 4-bromo-6-fluoronicotinic acid (C6H3BrFNO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-bromo-6-fluoronicotinic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H3BrFNO2 |
| Molecular Weight | 220.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related bromo Standards
- 6-Bromo-5-fluoropyridine-2-carboxylic Acid (CAS 1052714-46-1)
- 6-Bromo-4-fluoropicolinic acid (CAS 1060809-31-5)
- 6-Bromo-4-fluoronicotinic acid (CAS 1060809-33-7)
- 2-Bromo-4-fluoronicotinic acid (CAS 1060809-35-9)
- 3-Bromo-5-fluoropicolinic acid (CAS 1189513-55-0)
- 2-Bromo-3-fluoroisonicotinic Acid (CAS 1211530-89-0)
- 3-Bromo-4-fluoropicolinic acid (CAS 1211540-96-3)
- 5-Bromo-4-fluoropicolinic acid (CAS 1211582-26-1)
Recommended Standards
- 4-Bromo-2-fluoronicotinic acid (CAS 1256790-84-7)
- 4-Bromo-3-fluoropicolinic acid (CAS 1807209-95-5)
- 5-Bromo-2-fluoroisonicotinic Acid (CAS 1214377-40-8)
- 4-Bromo-3-fluoronitrobenzene (CAS 185331-69-5)
- Ethyl 3-methyl-5-phenyl-1H-pyrrole-2-carboxylate (CAS 81979-58-0)
- 3-Amino-N-(2,4-dichlorophenyl)benzamide (CAS 425650-72-2)
- Naphthalen-1-yl trifluoromethanesulfonate (CAS 99747-74-7)
- 7-Bromo-2,3-dihydrobenzo[b][1,4]dioxine-2-carbonitrile (CAS 1221072-56-5)
- 5-(2-Fluoropropan-2-yl)isoxazol-3-amine (CAS 1188908-86-2)
- (S)-5-Butyl-3-phenyl-2-thioxoimidazolidin-4-one (CAS 56710-94-2)
- 4-((2,5-Dibromophenyl)sulfonyl)morpholine (CAS 398996-97-9)
- 4-Methoxy-3-[(4-nitrophenyl)methoxy]benzaldehyde (CAS 341942-07-2)
- 3,5-Dichloro-3-fluoro-4-methoxybenzophenone (CAS 951886-12-7)
- [Ser]8-Acetylated Semaglutide (CAS CATO-C4X-2226218)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com