6-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2(1H)-one CAS 1269440-57-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1269440-57-4
Molecular FormulaC10H11IN4O
Molecular Weight330.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2(1H)-one CAS 1269440-57-4 chemical structure

Description

6-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2(1H)-one (CAS 1269440-57-4), molecular formula C10H11IN4O and molecular weight 330.13 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 6-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2(1H)-one (C10H11IN4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H11IN4O
Molecular Weight330.13 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentI-containing
Nitrogen Atoms4

Related Iodo Standards

Recommended Standards

Why CATO?