(S)-2-amino-2-(3-fluoro-2-(trifluoromethyl)pyridin-4-yl)acetic acid CAS 1269936-83-5
| CAS No. | 1269936-83-5 |
| Molecular Formula | C8H6F4N2O2 |
| Molecular Weight | 238.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (S)-2-amino-2-(3-fluoro-2-(trifluoromethyl)pyridin-4-yl)acetic acid (C8H6F4N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
(S)-2-amino-2-(3-fluoro-2-(trifluoromethyl)pyridin-4-yl)acetic acid (CAS 1269936-83-5) is a high-purity analytical reference standard with the molecular formula C8H6F4N2O2 and a molecular weight of 238.14 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (S)-2-amino-2-(3-fluoro-2-(trifluoromethyl)pyridin-4-yl)acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6F4N2O2 |
| Molecular Weight | 238.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related S Standards
- (R)-2-amino-2-(3-fluoro-2-(trifluoromethyl)pyridin-4-yl)acetic acid (CAS 1269914-11-5)
- 2-Amino-2-(3-fluoro-2-(trifluoromethyl)pyridin-4-yl)acetic acid (CAS 1270319-55-5)
- 2-Amino-5-fluoro-6-nitro-1h-indole-3-carboxamide (CAS 139495-88-8)
- 2-Amino-2-(2,4-dichloro-5-fluorophenyl)propan-1-ol (CAS 1184835-23-1)
- 3-Amino-3-(2,4-dichloro-5-fluorophenyl)propan-1-ol (CAS 1337620-14-0)
- 1-Amino-2-(2,4-dichloro-5-fluorophenyl)propan-2-ol (CAS 1406771-93-4)
- 4-Amino-5,8-difluoroquinoline-3-carbohydrazide (CAS 1315350-14-1)
- 8-Amino-4-bromonaphthalen-1-ol (CAS 2167185-67-1)
Recommended Standards
- 2-(2-Fluoro-4-(trifluoromethoxy)phenyl)acetic acid (CAS 1240256-95-4)
- 2-(4-Fluoro-2-(trifluoromethoxy)phenyl)acetic acid (CAS 1323966-19-3)
- 2-(3-Fluoro-4-(trifluoromethyl)phenyl)-2-hydroxyacetic acid (CAS 1214343-86-8)
- 5-Chloro-4-(2-chloroethyl)-3-methyl-1h-pyrazole-1-carbothioamide (CAS 1334147-79-3)
- 2-(4-Bromo-3-chloro-5-cyanophenyl)acetic acid (CAS 1805581-61-6)
- 3-chloro-5-(3,5-dichlorophenyl)-1,2,4-oxadiazole (CAS 1564515-67-8)
- 2,4-Dichloropyridin-3-ol (CAS 405141-76-6)
- 3-Phenylpicolinic acid (CAS 103863-15-6)
- (R)-5-Oxaspiro[3.5]nonan-8-amine (CAS 2201704-03-0)
- Terbutaline impurity 106 (CAS CATO-C4X-1183106)
- 2-(1-((1,3-Dimethyl-1H-pyrazol-5-yl)methyl)piperidin-4-yl)acetic acid (CAS 1171332-65-2)
- Imrecoxib Impurity 58 (CAS CATO-C4X-237958)
- 3,6-Dimethoxy-4-nitropyridazine (CAS 1881320-92-8)
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