(R)-1-(4-Chloro-2,5-difluorophenyl)ethan-1-amine CAS 1269983-63-2
| CAS No. | 1269983-63-2 |
| Molecular Formula | C8H8ClF2N |
| Molecular Weight | 191.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-1-(4-Chloro-2,5-difluorophenyl)ethan-1-amine.
(R)-1-(4-Chloro-2,5-difluorophenyl)ethan-1-amine (CAS 1269983-63-2) is a high-purity analytical reference standard with the molecular formula C8H8ClF2N and a molecular weight of 191.61 g/mol.
(R)-1-(4-Chloro-2,5-difluorophenyl)ethan-1-amine (C8H8ClF2N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (R)-1-(4-Chloro-2,5-difluorophenyl)ethan-1-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8ClF2N |
| Molecular Weight | 191.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 5-Chloroquinoline-8-carbaldehyde (CAS 1260794-21-5)
- 1-(3-Chlorophenyl)-2,2-difluoroethan-1-amine (CAS 1271477-83-8)
- 7-Chloroquinoline-8-carbaldehyde (CAS 1260759-71-4)
- 1-Chloroisoquinoline-8-carbaldehyde (CAS 1337879-86-3)
- Bisphenol S-2,2',3,3',5,5',6,6'-d8 (CAS 2483831-28-1)
- 3,6-Bis(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine (CAS 865658-06-6)
- Dibromo[μ-[1,1′-methylenebis[1,1-diphenylphosphine-κP]]]digold (CAS 72476-68-7)
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- 3-tert-Butyl-1-(2-chlorophenyl)-1h-pyrazole-4-carbaldehyde (CAS 1154284-12-4)
- 2-(6-Amino-5-(difluoromethyl)-2-fluoropyridin-3-yl)acetic acid (CAS 1806812-62-3)
- C-Peptide (Proinsulin) (CAS 59112-80-0)
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