(S)-1-(2-fluoro-3-(trifluoromethyl)phenyl)-2-methoxyethan-1-amine CAS 1270168-50-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1270168-50-7
Molecular FormulaC10H11F4NO
Molecular Weight237.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(S)-1-(2-fluoro-3-(trifluoromethyl)phenyl)-2-methoxyethan-1-amine CAS 1270168-50-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (S)-1-(2-fluoro-3-(trifluoromethyl)phenyl)-2-methoxyethan-1-amine.

(S)-1-(2-fluoro-3-(trifluoromethyl)phenyl)-2-methoxyethan-1-amine (CAS 1270168-50-7) is a high-purity analytical reference standard with the molecular formula C10H11F4NO and a molecular weight of 237.19 g/mol.

(S)-1-(2-fluoro-3-(trifluoromethyl)phenyl)-2-methoxyethan-1-amine (C10H11F4NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H11F4NO
Molecular Weight237.19 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms1

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