2-(3,4,5-Trifluorophenyl)azetidine CAS 1270412-77-5
| CAS No. | 1270412-77-5 |
| Molecular Formula | C9H8F3N |
| Molecular Weight | 187.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(3,4,5-Trifluorophenyl)azetidine (CAS 1270412-77-5), molecular formula C9H8F3N and molecular weight 187.16 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 2-(3,4,5-Trifluorophenyl)azetidine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 187.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(3,4,5-Trifluorophenyl)azetidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8F3N |
| Molecular Weight | 187.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluorophenyl Standards
- 1-(3,4,5-Trifluorophenyl)cyclopropan-1-amine (CAS 1248300-11-9)
- 3-(3,4,5-Trifluorophenyl)propanal (CAS 1036396-34-5)
- 3-(3,4,5-Trifluorophenyl)prop-2-en-1-ol (CAS 1280539-70-9)
- 1-(2,3,5-Trifluorophenyl)propan-2-one (CAS 1305323-99-2)
- 1-(3,4,5-Trifluorophenyl)propan-2-one (CAS 1305324-03-1)
- 1-(2,3,6-Trifluorophenyl)propan-2-one (CAS 1305324-34-8)
- 1-(2,3,4-Trifluorophenyl)propan-2-one (CAS 1305324-39-3)
- 1-(3,4,5-Trifluorophenyl)prop-2-en-1-ol (CAS 1494443-39-8)
Recommended Standards
- 2-{[2-(2,2,2-trifluoroethoxy)ethyl]amino}ethan-1-ol (CAS 1250809-76-7)
- 2-Cyclopropyl-6-(trifluoromethyl)pyridine (CAS 1321517-92-3)
- 5,6,7-Trifluoro-2,3-dihydro-1h-inden-1-amine (CAS 1337145-16-0)
- 2-Cyclopropyl-4-(trifluoromethyl)pyridine (CAS 1156542-33-4)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-chlorophenyl)propanoic acid (CAS 250740-51-3)
- 2-Chloro-6-methoxy-4-(trifluoromethyl)nicotinonitrile (CAS 1589549-33-6)
- 1203308-27-3 1-Cyclopropyl-1-(4-methylpyridin-2-yl)methanamine--hydrogen chloride (1/2) DTXSID50679008 (CAS 1203308-27-3)
- 1-(3,4-Dimethoxybenzyl)urea (CAS 65609-19-0)
- 3-(2-Fluoro-5-iodophenyl)acrylic acid (CAS 773130-25-9)
- 4-(methylsulfanyl)benzene-1-sulfonamide (CAS 3476-16-2)
- (1R,2S)-2-(2-oxo-2-(4-(trifluoromethyl)phenyl)ethyl)cyclopentane-1-carboxylic acid (CAS 733740-75-5)
- 4-tert-Butyl-N'-[(1E)-(3,5-dibromo-2-hydroxyphenyl)methylidene]benzohydrazide (CAS 328921-31-9)
- 7-Methyl-2-phenylindolizine (CAS 26557-56-2)
- Liraglutide Impurity 22 (CAS 536721-25-2)
Why CATO?
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