2,2,2-Trifluoro-1-(5-fluoropyridin-2-yl)ethan-1-amine CAS 1270575-81-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1270575-81-9
Molecular FormulaC7H6F4N2
Molecular Weight194.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,2,2-Trifluoro-1-(5-fluoropyridin-2-yl)ethan-1-amine CAS 1270575-81-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,2,2-Trifluoro-1-(5-fluoropyridin-2-yl)ethan-1-amine.

CATO supplies 2,2,2-Trifluoro-1-(5-fluoropyridin-2-yl)ethan-1-amine (CAS 1270575-81-9), a certified reference material (molecular formula C7H6F4N2, MW 194.13 g/mol) for analytical method development and quality control.

2,2,2-Trifluoro-1-(5-fluoropyridin-2-yl)ethan-1-amine (C7H6F4N2) contains a nitrile group, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H6F4N2
Molecular Weight194.13 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms2

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