4-Chloro-3-nitrophenyl isothiocyanate CAS 127142-66-9

Purity 97%+In StockPharmaceutical Standards
CAS No.127142-66-9
Molecular FormulaC7H3ClN2O2S
Molecular Weight214.63 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Chloro-3-nitrophenyl isothiocyanate CAS 127142-66-9 chemical structure

Description

The occurrence of 4-Chloro-3-nitrophenyl isothiocyanate is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 4-Chloro-3-nitrophenyl isothiocyanate (CAS 127142-66-9), a certified reference material (molecular formula C7H3ClN2O2S, MW 214.63 g/mol) for analytical method development and quality control.

4-Chloro-3-nitrophenyl isothiocyanate (C7H3ClN2O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 4-Chloro-3-nitrophenyl isothiocyanate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H3ClN2O2S
Molecular Weight214.63 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1993
Halogen ContentCl-containing
Nitrogen Atoms2
Sulfur Atoms1

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