Cinacalcet Impurity N26 CAS 1271930-12-1
| CAS No. | 1271930-12-1 |
| Molecular Formula | C22H28F3N |
| Molecular Weight | 363.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Cinacalcet Impurity N26 (CAS 1271930-12-1), a pharmacopoeial impurity reference standard (molecular formula C22H28F3N, MW 363.46 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C22H28F3N, Cinacalcet Impurity N26 contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 363.46 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H28F3N |
| Molecular Weight | 363.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Cinacalcet Standards
- Cinacalcet 7,8-Dihydro Racemate Base (CAS 802918-46-3)
- Cinacalcet Impurity 33 (CAS 802918-36-1)
- Cinacalcet Impurity 52 (CAS CATO-C4X-105952)
- Cinacalcet Impurity 90 (CAS CATO-C4X-105990)
- Cinacalcet Impurity 91 (CAS CATO-C4X-105991)
- Cinacalcet Impurity 34 (CAS 1025064-33-8)
- (R)-Cinacalcet-D3 (CAS 226256-56-0)
- Ent-Cinacalcet Hydrochloride (CAS 694495-47-1)
Recommended Standards
- 6-Benzyl-2-piperidin-2-yl-5,6,7,8-tetrahydro-1,4,6,9a-tetraaza-cyclopenta[b]naphthalen-9-ol (CAS 1229625-13-1)
- 4-((1H-Benzo[d]imidazol-2-yl)amino)-N-(2-(piperidin-1-yl)ethyl)benzamide (CAS 917763-80-5)
- 2-((1-Methyl-1H-tetrazol-5-yl)thio)-N-(2-(4-(methylsulfonyl)piperazin-1-yl)ethyl)acetamide (CAS 1206996-77-1)
- 5-((1,3-Diphenyl-1H-pyrazol-4-yl)methylene)-2-mercaptothiazol-4(5H)-one (CAS 380155-13-5)
- Nemonoxacin impurity 51 (CAS CATO-C4X-312851)
- Estradiol Impurity 59 (CAS CATO-C4X-163659)
- Cefpodoxime Impurity 62 (CAS CATO-C4X-157962)
- (R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole hydrochloride (CAS CATO-C4X-123090)
- Mosapride Impurity 62 (CAS CATO-C4X-104462)
- 5-Iodobenzene-1,3-dicarbaldehyde (CAS 859238-51-0)
- N-((5-(Benzo[d][1,3]dioxol-5-yl)isoxazol-3-yl)methyl)cyclopropanecarboxamide (CAS 1040639-14-2)
- (2E)-2-(4-Chlorophenyl)-3-[(3-chlorophenyl)amino]prop-2-enenitrile (CAS 338403-08-0)
- Cannabidiol hydroxyquinone (CAS 137252-25-6)
- Sperm Activating Peptide, Sea Urchin (CAS 140653-27-6)
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