Diethyl (2,4-difluorobenzyl)phosphonate CAS 127218-03-5
| CAS No. | 127218-03-5 |
| Molecular Formula | C11H15F2O3P |
| Molecular Weight | 264.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Diethyl (2,4-difluorobenzyl)phosphonate (C11H15F2O3P) contains a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Diethyl (2,4-difluorobenzyl)phosphonate (CAS 127218-03-5), molecular formula C11H15F2O3P and molecular weight 264.21 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Diethyl (2,4-difluorobenzyl)phosphonate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H15F2O3P |
| Molecular Weight | 264.21 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
Related Diethyl Standards
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Recommended Standards
- (2-Methoxy-5-(pentafluoro-lambda6-sulfanyl)phenyl)methanol (CAS 1240257-12-8)
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- 1-(4-Fluorophenyl)-4-methoxy-6-oxo-1,6-dihydropyridazine-3-carboxylic acid (CAS 1105193-26-7)
- 1-(3-Fluorophenyl)-4-methoxy-6-oxo-1,6-dihydropyridazine-3-carboxylic acid (CAS 1638612-42-6)
- 3,4-Dichloro-5-nitrobenzotrifluoride (CAS 657-02-3)
- 4-(4-Aminopiperidin-1-yl)tetrahydro-2H-thiopyran 1,1-dioxide (CAS 1156407-08-7)
- Pyrazolo[1,5-a]pyrimidine-3-sulfonyl chloride (CAS 1642583-15-0)
- (3S,4S)-4-propylpyrrolidin-3-ol (CAS 1932343-12-8)
- 4-(2-(4-Bromophenyl)-1,2-diphenylvinyl)phenol (CAS 1801839-74-6)
- 4-(4-Methylbenzoyl)-N-[(pyridin-3-yl)methyl]-1H-pyrrole-2-carboxamide (CAS 439111-62-3)
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