N-(4-acetylphenyl)-2-phenoxyacetamide CAS 127221-07-2
| CAS No. | 127221-07-2 |
| Molecular Formula | C16H15NO3 |
| Molecular Weight | 269.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-(4-acetylphenyl)-2-phenoxyacetamide (C16H15NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies N-(4-acetylphenyl)-2-phenoxyacetamide (CAS 127221-07-2), a certified reference material (molecular formula C16H15NO3, MW 269.30 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H15NO3 |
| Molecular Weight | 269.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 1 |
Related N Standards
- n-(3-Acetylphenyl)-2-methoxybenzamide (CAS 314022-80-5)
- N-(3-acetylphenyl)-2-phenoxyacetamide (CAS 303794-79-8)
- n-(3-Acetylphenyl)-3-methoxybenzamide (CAS 341020-22-2)
- N-(3-acetylphenyl)-4-methoxybenzamide (CAS 316150-74-0)
- N-(4-Acetylphenyl)-3-methoxybenzamide (CAS 341020-53-9)
- N-(4-acetylphenyl)-4-methoxybenzamide (CAS 72269-25-1)
- N-(4-acetylphenyl)-2-bromopropanamide (CAS 1171221-51-4)
- N-(4-acetylphenyl)-3-bromopropanamide (CAS 889953-55-3)
Recommended Standards
- Formoterol Impurity 28 (CAS 126587-86-8)
- Ethyl 8-cyano-4-(dimethylamino)quinoline-3-carboxylate (CAS 1279209-06-1)
- 2',4',6'-Trimethoxy-[1,1'-biphenyl]-4-carbonitrile (CAS 1262967-17-8)
- Ethyl 4-((tert-butoxycarbonyl)amino)-1-methyl-1H-imidazole-2-carboxylate (CAS 128293-63-0)
- Ethyl 2-(2-cyanopyridin-3-yl)acetate (CAS 3423-45-8)
- (4-Chloro-3-fluorophenyl)(thiophen-2-yl)methanol (CAS 1343108-21-3)
- CAS 89947-80-8 (CAS 89947-80-8)
- 2-(propylamino)acetonitrile (CAS 16728-81-7)
- 3-(4-Fluorophenyl)picolinic acid (CAS 1192608-90-4)
- tert-butyl 4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)piperidine-1-carboxylate (CAS 1334494-13-1)
- 1-(3-Chlorophenyl)-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carbonitrile (CAS 175134-97-1)
- N-(4-(Benzofuran-2-yl)thiazol-2-yl)pentanamide (CAS 923440-44-2)
- 4-(3,4-Dimethoxybenzylidene)-1-(2-methoxy-4-nitrophenyl)-2-methyl-1H-imidazol-5(4H)-one (CAS 78311-94-1)
- Myristoyl Pentapeptide -4 acetate (CAS 959610-30-1(free base))
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