2-methyl-4-[(2R)-pyrrolidin-2-yl]-1,3-thiazole CAS 1272728-02-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-methyl-4-[(2R)-pyrrolidin-2-yl]-1,3-thiazole.

2-methyl-4-[(2R)-pyrrolidin-2-yl]-1,3-thiazole (CAS 1272728-02-5), molecular formula C8H12N2S and molecular weight 168.26 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, 2-methyl-4-[(2R)-pyrrolidin-2-yl]-1,3-thiazole is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 168.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-methyl-4-[(2R)-pyrrolidin-2-yl]-1,3-thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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