Ethyl 2-amino-5-(trifluoromethyl)-2,3-dihydro-1H-indene-2-carboxylate hydrochloride CAS 1272758-27-6
| CAS No. | 1272758-27-6 |
| Molecular Formula | C13H14F3NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 2-amino-5-(trifluoromethyl)-2,3-dihydro-1H-indene-2-carboxylate hydrochloride.
Ethyl 2-amino-5-(trifluoromethyl)-2,3-dihydro-1H-indene-2-carboxylate hydrochloride (CAS 1272758-27-6) is a high-purity analytical reference standard with the molecular formula C13H14F3NO2HCl and a molecular weight of 309.71 g/mol.
The molecular framework of Ethyl 2-amino-5-(trifluoromethyl)-2,3-dihydro-1H-indene-2-carboxylate hydrochloride (C13H14F3NO2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 2-amino-5-(trifluoromethyl)-2,3-dihydro-1H-indene-2-carboxylate hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H14F3NO2 HCl |
| Molecular Weight | 309.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 3-Amino-1-methyl-4-phenoxyindazole (CAS 1000018-07-4)
- 3-Amino-2,6-dibromo-5-ethoxypyridine (CAS 1000018-10-9)
- Methyl 2-amino-5-bromo-4-isopropylbenzoate (CAS 1000018-13-2)
- Methyl 2-amino-3-(pyridin-2-yl)propanoate (CAS 100002-84-4)
- 100005-23-0 2-Amino-4-(4-methoxyphenyl)-5-methylthiophene-3-carbonitrile 7050AC C13H12N2OS (CAS 100005-23-0)
- Methyl 1-amino-4-cyano-1H-pyrrole-2-carboxylate (CAS 1000313-12-1)
- 6-Amino-7-hydroxy-2,3-dihydro-1H-inden-1-one hydrobromide (CAS 1000333-87-8)
- 6-Amino-7-iodo-2,3-dihydro-1H-inden-1-one (CAS 1000333-93-6)
Recommended Standards
- 1365962-04-4 2-Chloro-N-(3-cyano-6-phenyl-4,5,6,7-tetrahydro-1-benzothien-2-yl)propanamide MFCD22056597 (CAS 1365962-04-4)
- 2-[(1S)-1-methoxyethyl]-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 2641451-45-6)
- 5-Isobenzofurancarboxylic acid, 1,3-dihydro-1,3-dioxo-, polymer with 4,4'-oxybis[benzenamine] and 4,4'-[sulfonylbis(4,1-phenyleneoxy)]bis[benzenamine] (CAS 72968-66-2)
- 2-Benzyl-1H-benzoimidazol-5-ylamine hydrochloride (CAS 110178-73-9)
- (1S,2R)-HIF-2α-IN-2 (CAS 1672666-80-6)
- 6-Ethyl-5H-pyrrolo[3,4-b]pyridin-7(6H)-one (CAS 1046121-01-0)
- Methyl 4-[3-(benzyloxy)phenyl]-2-chlorobenzoate (CAS 1820712-00-2)
- 5-(1H-Pyrazol-5-yl)thiophene-2-carbaldehyde (CAS 1015939-92-0)
- 2-(4-(Trifluoromethyl)phenyl)cyclopropanamine hydrochloride (CAS 2711-55-9)
- Tau Peptide (304-318) trifluoroacetate salt (CAS 330456-49-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com