tert-Butyl 3-fluoro-3-(1-hydroxycyclopropyl)azetidine-1-carboxylate CAS 1273563-62-4
| CAS No. | 1273563-62-4 |
| Molecular Formula | C11H18FNO3 |
| Molecular Weight | 231.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including tert-Butyl 3-fluoro-3-(1-hydroxycyclopropyl)azetidine-1-carboxylate.
CATO supplies tert-Butyl 3-fluoro-3-(1-hydroxycyclopropyl)azetidine-1-carboxylate (CAS 1273563-62-4), a certified reference material (molecular formula C11H18FNO3, MW 231.26 g/mol) for analytical method development and quality control.
tert-Butyl 3-fluoro-3-(1-hydroxycyclopropyl)azetidine-1-carboxylate (C11H18FNO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H18FNO3 |
| Molecular Weight | 231.26 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Tert-butyl 2-(fluoromethyl)-4-oxopiperidine-1-carboxylate (CAS 1260674-52-9)
- 4-{[(Dimethylamino)methyl]amino}-7-methylpyrazolo-[5,1-c][1,2,4]triazine-3-carbonitrile (CAS 1306738-66-8)
- (S)-2,2,2-Trifluoro-1-(2,3,4,5-tetramethylphenyl)ethan-1-amine (CAS 1241676-91-4)
- 2,2-Dimethyl-3-(3-(trifluoromethyl)phenyl)propan-1-amine (CAS 1344235-44-4)
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- tert-Butyl 4-(2-hydroxypropyl)piperazine-1-carboxylate (CAS 745738-05-0)
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- 6-Ethoxy-2-methyl-1,3-benzothiazole (CAS 18879-72-6)
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- Phenytoin Impurity 1 (CAS 61693-07-0)
- 4-(2-Ethynylphenyl)morpholine (CAS 2098805-05-9)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
Why CATO?
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