1-(2-Bromo-4,5-difluorophenyl)ethanone CAS 127371-55-5
| CAS No. | 127371-55-5 |
| Molecular Formula | C8H5BrF2O |
| Molecular Weight | 235.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, 1-(2-Bromo-4,5-difluorophenyl)ethanone is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 235.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-(2-Bromo-4,5-difluorophenyl)ethanone (CAS 127371-55-5), molecular formula C8H5BrF2O and molecular weight 235.03 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(2-Bromo-4,5-difluorophenyl)ethanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5BrF2O |
| Molecular Weight | 235.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 4'-Bromo-2',3'-difluoroacetophenone (CAS 1007346-28-2)
- 3’-Bromo-2’,4’-difluoroacetophenone (CAS 1210824-63-7)
- 4-Bromo-2,5-difluoroacetophenone, 97% (CAS 123942-11-0)
- 5-Bromo-2,4-difluoro-3-methylbenzaldehyde (CAS 1378865-38-3)
- 5-Bromo-2-(2,2-difluorocyclopropyl)pyrimidine (CAS 1393572-03-6)
- 1-(4-Bromo-3,5-difluorophenyl)ethanone (CAS 1528607-78-4)
- 1-(6-Bromo-2,3-difluorophenyl)ethanone (CAS 1542563-93-8)
- 4-Bromo-1-(difluoromethyl)-5-methyl-1H-pyrrole-2-carbonitrile (CAS 1559064-11-7)
Recommended Standards
- 4-Iodo-5-methylpyrimidin-2-amine (CAS 1260741-48-7)
- 5-Iodo-2-methylpyrimidin-4-amine (CAS 1239738-87-4)
- Methyl 2-(3-bromofuran-2-yl)-2-hydroxyacetate (CAS 1479928-19-2)
- N,N'-(4,6-Dichloropyrimidine-2,5-diyl)diformamide (CAS 116477-30-6)
- Potassiumtrifluoro(3-(2-hydroxyethyl)phenyl)borate (CAS 1015082-80-0)
- 4-fluorotetrahydrofuran-3-sulfonyl chloride (CAS 1803609-87-1)
- 6-Chloro-2-ethoxypyrimidin-4-amine (CAS 3286-56-4)
- 1-Methylisoquinoline-3-carbaldehyde (CAS 1500249-21-7)
- 7-Hydroxyfuro[3,2-b]pyridine (CAS 1533781-17-7)
- (Sp)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl benzyl(3',6'-dihydroxy-[1,1':4',1''-terphenyl]-2'-yl)phosphinate (CAS 1420992-15-9)
- 3-(Bromomethyl)-2-(trifluoromethyl)-1,1'-biphenyl (CAS 2323625-45-0)
- Phenytoin Impurity 18 (CAS CATO-C4X-186418)
- 1-Bromonaphthalene (CAS 90-11-9)
- Des-Ile27-Tirzepatide (CAS CATO-CPTD788946)
Why CATO?
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