5-[(3,5-Dimethoxyphenyl)methylene]-2-thioxo-4-thiazolidinone CAS 127378-29-4
| CAS No. | 127378-29-4 |
| Molecular Formula | C12H11NO3S2 |
| Molecular Weight | 281.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-[(3,5-Dimethoxyphenyl)methylene]-2-thioxo-4-thiazolidinone (CAS 127378-29-4) is a high-purity analytical reference standard with the molecular formula C12H11NO3S2 and a molecular weight of 281.35 g/mol.
Structurally, 5-[(3,5-Dimethoxyphenyl)methylene]-2-thioxo-4-thiazolidinone (C12H11NO3S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 281.35 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11NO3S2 |
| Molecular Weight | 281.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
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Recommended Standards
- (5E)-5-(2,5-Dimethoxybenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one (CAS 127378-17-0)
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- Benzyl 3,8-diazabicyclo[3.2.1]octane-3-carboxylate (CAS 415979-31-6)
- 2-CYCLOHEXYLPIPERIDINE HCL (CAS 51523-81-0)
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- Des-Gln24-Tirzepatide (CAS CATO-CPTD788949)
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