N-(3-Formyl-5-methylpyridin-2-yl)pivalamide CAS 127446-31-5
| CAS No. | 127446-31-5 |
| Molecular Formula | C12H16N2O2 |
| Molecular Weight | 220.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(3-Formyl-5-methylpyridin-2-yl)pivalamide (C12H16N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
N-(3-Formyl-5-methylpyridin-2-yl)pivalamide (CAS 127446-31-5), molecular formula C12H16N2O2 and molecular weight 220.27 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16N2O2 |
| Molecular Weight | 220.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 2 |
Related N Standards
- N-(3-formyl-4-methylpyridin-2-yl)-2,2-dimethylpropanamide (CAS 216678-81-8)
- 3-Formyl-2,4,6-trimethylbenzyl acetate (CAS 137380-48-4)
- 5-Formyl-4-(4-MethylpyriDin-1-ium-1-yl)-2-oxothiazol-3-ide (CAS 127868-42-2)
- 4-Formyl-2-methoxyphenyl cyclopropanecarboxylate (CAS 380336-99-2)
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- 4-Formyl-7-methoxy-1-benzofuran-2-carboxylic acid (CAS 7795-71-3)
- Methyl 5-(2-formyl-1H-pyrrol-1-yl)-1H-1,2,4-triazole-3-carboxylate (CAS 554402-33-4)
- 6-Formyl-4-methylpyridine-2-sulfonyl chloride (CAS 1393545-97-5)
Recommended Standards
- Methyl 5-(piperidin-2-yl)nicotinate (CAS 1270517-08-2)
- 2-(Tert-butyl)-4-cyclopropylpyrimidine-5-carboxylic acid (CAS 1291787-37-5)
- 6-[(2r)-1-hydroxy-3-methylbutan-2-yl]-5h,6h,7h-pyrrolo[3,4-b]pyridin-5-one (CAS 1268952-43-7)
- 8-Phenylnaphthalen-1-ol (CAS 129957-20-6)
- 6-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid (CAS 952182-22-8)
- 3-(o-Tolyl)propan-1-ol (CAS 14902-36-4)
- Imidazo[1,2-a]pyrazine-8-carboxylic acid hydrochloride (CAS 1820735-11-2)
- 2-(5-Chlorothiophen-2-yl)propanoic acid (CAS 1215995-07-5)
- Benzyl (2-(ethylamino)-2-oxoethyl)carbamate (CAS 21855-73-2)
- 4-Hydroxy-3-(2-(5-methoxy-1H-indol-3-yl)ethyl)-4-methyl-1-oxa-3-azaspiro[4.5]Decan-2-one (CAS 883291-32-5)
- tert-Butyl n-[(5-methylpyrrolidin-3-yl)methyl]carbamate (CAS 1374653-91-4)
- 3-(4-Piperidinyl)propionic Acid (CAS 1822-32-8)
- Oryzanol Impurity 17 (CAS 286011-27-6)
- Casein Kinase II Receptor Peptide (CAS 198481-81-1)
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