Pyrimidine-2,5-dicarboxylic acid CAS 127527-24-6
| CAS No. | 127527-24-6 |
| Molecular Formula | C6H4N2O4 |
| Molecular Weight | 168.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Pyrimidine-2,5-dicarboxylic acid (CAS 127527-24-6) is a high-purity analytical reference standard with the molecular formula C6H4N2O4 and a molecular weight of 168.11 g/mol.
Pyrimidine-2,5-dicarboxylic acid (C6H4N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Pyrimidine-2,5-dicarboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4N2O4 |
| Molecular Weight | 168.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 2 |
Related Pyrimidine Standards
- Pyrimidine-4,5-dicarboxylic acid (CAS 54001-63-7)
- Pyrimidine,2-ethenyl-4,6-dimethoxy- (CAS 850234-80-9)
- Pyrimidine-4,6-dicarboxamide (CAS 6345-42-2)
- 34171-43-2 Pyrimidine, 2-chloro-4-(dimethylamino)-5-methyl- 5-25-10-00196 (Beilstein Handbook Reference) BRN 0608293 4-Pyrimidinamine, 2-chloro-N,N,5-trimethyl- (CAS 34171-43-2)
- 1,1'-(Pyrimidine-4,6-diyl)diethanone (CAS 210295-82-2)
- Pyrimidine-2,4,6-tricarbaldehyde (CAS 1209493-65-1)
- 5909-26-2 Pyrimidine, 2,4-bis(methylthio)- DTXSID40344713 (CAS 5909-26-2)
- Pyrimidine-2-sulfonyl fluoride (CAS 35762-87-9)
Recommended Standards
- 2-(3-Chloro-2-fluorophenyl)pyrrolidine (CAS 1260802-03-6)
- 2,2,2-Trifluoro-1-(tetrahydro-3-furanyl)ethanone (CAS 1339862-66-6)
- trans-3-(trifluoromethyl)cyclobutanecarboxylic acid (CAS 123812-83-9)
- 1,1,1-Trifluoro-4-methoxy-,(3e)-3-penten-2-one (CAS 135351-20-1)
- 1-Ethyl-2-imino-N-methyl-5-oxo-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide (CAS 371134-80-4)
- 4-Chloro-2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidineHydrochloride (CAS 647863-08-9)
- 3-[(3,4-Dimethylphenoxy)methyl]pyrrolidinehydrochloride (CAS 1219980-95-6)
- Ethyl 5-ethylthiophene-2-carboxylate (CAS 773135-08-3)
- 4-[2-(2,4-difluorophenyl)ethyl]piperidine hydrochloride (CAS 148135-97-1)
- 3-Bromo-2-((2-(4-bromophenyl)-2-oxoethylidene)amino)-9H-fluoren-9-one (CAS 3405-16-1)
- 2-Bromo-1-((2R,5S)-2,5-dimethylpyrrolidin-1-yl)ethanone (CAS 157905-03-8)
- 1-(Morpholin-4-yl)-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)propan-1-one (CAS 2377607-67-3)
- (5-Ethynylthiophen-2-yl)methanol (CAS 1631739-82-6)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
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