5-bromo-2-(2,4-difluorophenoxy)pyrimidine CAS 1275282-76-2
| CAS No. | 1275282-76-2 |
| Molecular Formula | C10H5BrF2N2O |
| Molecular Weight | 287.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-bromo-2-(2,4-difluorophenoxy)pyrimidine.
5-bromo-2-(2,4-difluorophenoxy)pyrimidine (CAS 1275282-76-2), molecular formula C10H5BrF2N2O and molecular weight 287.06 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-bromo-2-(2,4-difluorophenoxy)pyrimidine (C10H5BrF2N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 287.06 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H5BrF2N2O |
| Molecular Weight | 287.06 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related bromo Standards
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- 4-Bromo-2-fluoro-1-((2,2,2-trifluoroethoxy)methyl)benzene (CAS 1247562-38-4)
- 2-Bromo-4-fluoro-1-((2,2,2-trifluoroethoxy)methyl)benzene (CAS 1248443-45-9)
- 2-(4-Bromo-3-nitro-1h-pyrazol-1-yl)-N-(prop-2-yn-1-yl)acetamide (CAS 1249602-39-8)
- 2-{3-bromo-1-methyl-4-oxo-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-5-yl}acetic acid (CAS 1251924-18-1)
- 3-(4-Bromo-2-fluorophenyl)-1,1,1-trifluoropropan-2-ol (CAS 1340535-60-5)
- 3-(3-Bromo-4-fluorophenyl)-1,1,1-trifluoropropan-2-ol (CAS 1342246-93-8)
Recommended Standards
- 3-Hydrazono-4-iodoindolin-2-one (CAS 1198595-66-2)
- 3-(2,4-Dichlorophenyl)-4,4,4-trifluorobutanoic acid (CAS 1284040-10-3)
- 3-Iodoimidazo[1,2-a]pyridine-7-carboxamide (CAS 1036990-62-1)
- 3-(3,4-Dichlorophenyl)-4,4,4-trifluorobutanoic acid (CAS 1285309-36-5)
- 5-(Tert-butyl) 6-methyl (6S)-1,1-difluoro-5-azaspiro[2.4]Heptane-5,6-dicarboxylate (CAS 1701433-61-5)
- tert-Butyl 4-(((2-aminoethyl)thio)methyl)piperidine-1-carboxylate (CAS 1353976-72-3)
- 2-(2,4,6-Triisopropylphenyl)acetic acid (CAS 4276-85-1)
- 2-((4-Iodo-1H-pyrazol-1-yl)methyl)-5-methyl-1,3,4-oxadiazole (CAS 1343754-63-1)
- N-(4-Methoxyphenyl)-2-(4-nitrophenoxy)acetamide (CAS 303795-97-3)
- (Rac)-ALX 5407 (CAS 405225-21-0)
- 6-methyl-1H-spiro[2,1-benzoxaborole-3,1’-cyclopentane]-1-ol (CAS 1437052-32-8)
- 1-(3-(Pyridin-2-yl)-1,2,4-oxadiazol-5-yl)ethan-1-amine (CAS 936940-60-2)
- Ceritinib Impurity 10 (CAS CATO-C4X-104810)
- SV40 Nuclear Transport Signal Peptide Analog (CAS 104914-40-1)
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