(R)-6-(3-Fluoro-benzyloxy)-N-(1,2,2-trimethyl-propyl)-nicotinamide CAS 1276013-77-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1276013-77-4
Molecular FormulaC19H23FN2O2
Molecular Weight330.40 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(R)-6-(3-Fluoro-benzyloxy)-N-(1,2,2-trimethyl-propyl)-nicotinamide CAS 1276013-77-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 330.40 g/mol gives (R)-6-(3-Fluoro-benzyloxy)-N-(1,2,2-trimethyl-propyl)-nicotinamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(R)-6-(3-Fluoro-benzyloxy)-N-(1,2,2-trimethyl-propyl)-nicotinamide (CAS 1276013-77-4), molecular formula C19H23FN2O2 and molecular weight 330.40 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (R)-6-(3-Fluoro-benzyloxy)-N-(1,2,2-trimethyl-propyl)-nicotinamide (C19H23FN2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC19H23FN2O2
Molecular Weight330.40 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms2

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