Ethyl 5-(4-fluorophenyl)thiazole-4-carboxylate CAS 127918-22-3

Purity 97%+In StockPharmaceutical Standards
CAS No.127918-22-3
Molecular FormulaC12H10FNO2S
Molecular Weight251.28 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 5-(4-fluorophenyl)thiazole-4-carboxylate CAS 127918-22-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 251.28 g/mol gives Ethyl 5-(4-fluorophenyl)thiazole-4-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Ethyl 5-(4-fluorophenyl)thiazole-4-carboxylate (CAS 127918-22-3), a certified reference material (molecular formula C12H10FNO2S, MW 251.28 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Ethyl 5-(4-fluorophenyl)thiazole-4-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 251.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures Ethyl 5-(4-fluorophenyl)thiazole-4-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H10FNO2S
Molecular Weight251.28 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1993
Halogen ContentF-containing
Nitrogen Atoms1
Sulfur Atoms1

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