3-(3-Chloro-4-fluorophenyl)-1H-1,2,4-triazol-5-amine CAS 1279219-23-6
| CAS No. | 1279219-23-6 |
| Molecular Formula | C8H6ClFN4 |
| Molecular Weight | 212.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(3-Chloro-4-fluorophenyl)-1H-1,2,4-triazol-5-amine.
3-(3-Chloro-4-fluorophenyl)-1H-1,2,4-triazol-5-amine (CAS 1279219-23-6) is a high-purity analytical reference standard with the molecular formula C8H6ClFN4 and a molecular weight of 212.61 g/mol.
3-(3-Chloro-4-fluorophenyl)-1H-1,2,4-triazol-5-amine (C8H6ClFN4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(3-Chloro-4-fluorophenyl)-1H-1,2,4-triazol-5-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClFN4 |
| Molecular Weight | 212.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 5-(4-Chloro-2-fluorophenyl)-4h-1,2,4-triazol-3-amine (CAS 1016677-08-9)
- 3-(2-Chloro-6-fluorophenyl)isoxazol-5-amine (CAS 1021143-64-5)
- 3-(5-Chloro-2-fluorophenyl)isoxazol-5-amine (CAS 1021245-63-5)
- 2-(2-Chloro-4-fluorophenyl)-5-methyl-1,3,4-oxadiazole (CAS 1171930-74-7)
- 5-Chloro-3-[(4-fluorophenyl)methyl]-1,2,4-oxadiazole (CAS 1247677-00-4)
- N-(4-chloro-3-fluorophenyl)-2-cyanoacetamide (CAS 1306950-43-5)
- 1-(4-Chloro-3-fluoro-1H-pyrrolo[2,3-b]pyridin-1-yl)ethan-1-one (CAS 1352393-92-0)
- 2-chloro-5-[(4-fluorophenyl)methyl]-1,3,4-oxadiazole (CAS 1368427-75-1)
Recommended Standards
- 2-(Chloromethyl)-5-fluoroquinazolin-4(3H)-one (CAS 1263413-73-5)
- 5-(Chloromethyl)-3-(2-fluorophenyl)-1,2,4-oxadiazole (CAS 110704-45-5)
- 3-chloro-5-[(4-fluorophenyl)methyl]-1,2,4-oxadiazole (CAS 1393562-57-6)
- 5-(Chloromethyl)-1-(3-fluorophenyl)-1h-1,2,3,4-tetrazole (CAS 1105194-91-9)
- 6-(4-Bromo-3-methylphenoxy)hexanenitrile (CAS 1443343-02-9)
- (Methylthio)dichloromethane (CAS 2032-76-0)
- 3-[(4-Bromophenyl)(hydroxy)methyl]isoxazole-4-carboxylic Acid (CAS 2006276-91-9)
- trans-2-[4-(Trifluoromethoxy)phenyl]cyclopropanecarboxylic Acid (CAS 238431-33-9)
- 2-(2-Chloro-4,5-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2121514-02-9)
- (((1-Ethynylcyclopropyl)methoxy)methyl)benzene (CAS 2068725-75-5)
- 3-(3-Amino-4-chloro-1h-pyrazol-1-yl)propanoic acid (CAS 1006455-70-4)
- Methyl 1-phenyl-9H-pyrido[3,4-b]indole-3-carboxylate (CAS 81677-50-1)
- 2-(tert-butoxy)-2-oxoacetonitrile (CAS 57022-34-1)
- Semaglutide (CAS 910463-68-2（free base）)
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