2-Amino-7-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile CAS 127945-75-9
| CAS No. | 127945-75-9 |
| Molecular Formula | C11H13N5O4 |
| Molecular Weight | 279.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2-Amino-7-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (CAS 127945-75-9), a certified reference material (molecular formula C11H13N5O4, MW 279.25 g/mol) for analytical method development and quality control.
2-Amino-7-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (C11H13N5O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H13N5O4 |
| Molecular Weight | 279.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 5 |
Related Amino Standards
- (Z)-5-Amino-3-(2-(benzo[d][1,3]dioxol-5-yl)-1-cyanovinyl)-1H-pyrazole-4-carbonitrile (CAS 354158-98-8)
- 1-(4-Amino-5-oxo-5,6,7,8-tetrahydropyrimido[5,4-f][1,4]oxazepin-2-yl)azetidine-3-carboxylic acid (CAS 2306277-40-5)
- 5-Amino-6-cyano-7-phenylisoxazolo[4,5-b]pyridine-3-carboxamide (CAS 76390-75-5)
- Ethyl 2-(7-amino-5-hydroxy-1-methyl-4-oxo-1,4-dihydropyrimido[4,5-c]pyridazin-3-yl)acetate (CAS 67873-35-2)
- 2-Amino-4,5-dimethyl-1-(4-(trifluoromethyl)phenyl)-1H-pyrrole-3-carbonitrile (CAS 1094407-06-3)
- methyl 2-amino-4-fluoro-5-(4-fluorophenoxy)benzoate (CAS 1333657-08-1)
- (1-(4-Amino-1,2,5-oxadiazol-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl)(morpholino)methanone (CAS 312285-86-2)
- 1-(4-Amino-1,2,5-oxadiazol-3-yl)-5-(pyrrolidin-1-ylmethyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 352446-61-8)
Recommended Standards
- 7-Phenyl-1-(prop-2-ynyl)-1H-pyrimido-[4,5-d][1,3]oxazine-2,4-dione (CAS 1253790-88-3)
- 1-Hydroxy-2-(2-nitrophenyl)-1H-indole-3-carbonitrile (CAS 13713-11-6)
- 8-(3-Phenyl-1,2,4-oxadiazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol (CAS 1239755-06-6)
- 2-Nitro-5H-indolo[3,2-c]quinolin-6(11H)-one (CAS 1418414-05-7)
- Tert-butyl n-methyl-N-(pyrrolidin-2-ylmethyl)carbamate (CAS 1334335-95-3)
- 1-(1,1,3,3,6-Pentamethyl-7-nitro-2,3-dihydro-1H-inden-5-yl)imidazolidin-2-one (CAS 1209101-05-2)
- Methyl 4-bromo-2-cyano-3-formylbenzoate (CAS 1805592-47-5)
- Mirogabalin Impurity 163 (CAS CATO-C4X-2924163)
- Tivozanib Impurity 18 (CAS CATO-C4X-340018)
- (R)-2-((tert-butoxycarbonyl)amino)-3-(1-tosyl-1H-imidazol-4-yl)propanoic acid (CAS 69541-68-0)
- (2-Amino-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)(piperidin-1-yl)methanone (CAS 512826-70-9)
- tert-Butyl 4-(6-methoxypyrimidin-4-yl)-2-methylpiperazine-1-carboxylate (CAS 1353954-72-9)
- 2-(Cyclopentylamino)-2-oxo-1-phenylethyl isoxazole-5-carboxylate (CAS 606102-35-6)
- Semaglutide impurity 208 (CAS CATO-C4X-2226208)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com