4-Isopropyl-2-methylpyrimidine CAS 127958-18-3
| CAS No. | 127958-18-3 |
| Molecular Formula | C8H12N2 |
| Molecular Weight | 136.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Isopropyl-2-methylpyrimidine (CAS 127958-18-3), molecular formula C8H12N2 and molecular weight 136.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Isopropyl-2-methylpyrimidine (C8H12N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 4-Isopropyl-2-methylpyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H12N2 |
| Molecular Weight | 136.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 2 |
Related Isopropyl Standards
- 5-Isopropyl-3-methylpyridazine (CAS 135216-82-9)
- 2-Isopropyl-5-methylpyrazine (CAS 13925-05-8)
- 2-Isopropyl-3-methylpyrazine (CAS 15986-81-9)
- 2-Isopropyl-4-methylpyrimidine (CAS 74502-86-6)
- 2-Isopropyl-6-methylpyrazine (CAS 24541-74-0)
- 5-Isopropyl-2-methylpyrimidine (CAS 64171-54-6)
- Ethyl isopropyl sulfone (CAS 4853-75-2)
- N-Isopropyl-2-chloroacetamide (CAS 2895-21-8)
Recommended Standards
- 1-(5-methylpyridin-3-yl)ethan-1-amine (CAS 1270526-80-1)
- (S)-5,6,7,8-Tetrahydroindolizin-7-amine (CAS 128916-00-7)
- 3-(Aminomethyl)-5-methylaniline (CAS 1261641-72-8)
- 3-(1-Aminoethyl)aniline (CAS 129725-48-0)
- N-(2,5-dimethylphenyl)-1-phenylcyclopentane-1-carboxamide (CAS 1023575-42-9)
- 3-Chloro-2,6-dimethyl-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 87273-59-4)
- 2,2,2-Trifluoro-N-(5-(N-(thiazol-2-yl)sulfamoyl)quinolin-8-yl)acetamide (CAS 928825-79-0)
- 3-Methyl-4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylic acid (CAS 847783-61-3)
- Methyl (R)-2-(6-(trifluoromethyl)-2,3-dihydrobenzofuran-3-yl)acetate (CAS 2831899-39-7)
- Tert-butyl 4-((1r,4r)-4-aminocyclohexyl)piperazine-1-carboxylate (CAS 876371-20-9)
- 4-Chloro-5-(difluoromethyl)-6-morpholinopyrimidin-2-amine (CAS 2149598-74-1)
- trans-3-Methyl-4-(phenylamino)-1-(phenylmethyl)-4-piperidinecarbonitrile (CAS 147292-25-9)
- 1,1-Dibutoxy-N,N-dimethylmethanamine (CAS 18503-90-7)
- Semaglutide Impurity 82 (CAS CATO-C4X-222682)
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