3-Chloro-1-methyl-5-(trifluoromethyl)pyridin-2(1H)-one CAS 1281189-85-2
| CAS No. | 1281189-85-2 |
| Molecular Formula | C7H5ClF3NO |
| Molecular Weight | 211.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-Chloro-1-methyl-5-(trifluoromethyl)pyridin-2(1H)-one (CAS 1281189-85-2) is a high-purity analytical reference standard with the molecular formula C7H5ClF3NO and a molecular weight of 211.57 g/mol.
Based on its molecular formula C7H5ClF3NO, 3-Chloro-1-methyl-5-(trifluoromethyl)pyridin-2(1H)-one contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 211.57 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5ClF3NO |
| Molecular Weight | 211.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 6-Chloro-N-methyl-2-(trifluoromethyl)pyrimidin-4-amine (CAS 1023813-53-7)
- (3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methanol (CAS 1033463-31-8)
- (6-Chloro-5-(trifluoromethyl)pyridin-3-yl)methanol (CAS 1113049-91-4)
- 6-Chloro-5-(trifluoromethyl)pyridine-2,3-diamine (CAS 114087-45-5)
- 2-Chloro-6-methoxy-4-(trifluoromethyl)pyridine (CAS 1160994-99-9)
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- (2-Chloro-6-trifluoromethyl-pyridin-4-yl)-methanol (CAS 1196157-41-1)
- 2-Chloro-4-methoxy-6-(trifluoromethyl)pyridine (CAS 1211539-69-3)
Recommended Standards
- 1-(2-Chloro-4-pyridyl)-2,2,2-trifluoroethanol (CAS 1263400-50-5)
- 2-Chloro-6-hydrazinyl-4-(trifluoromethyl)pyridine (CAS 129015-68-5)
- 2-Chloro-6-(trifluoromethoxy)aniline (CAS 1261673-70-4)
- 5-Chloro-2-hydrazinyl-3-(trifluoromethyl)pyridine (CAS 129015-69-6)
- 7-Iodo-5-(trifluoromethyl)indoline-2,3-dione (CAS 1067187-92-1)
- 5-Chloro-6-methyl-7H-pyrrolo[2,3-b]pyridine-3-carbaldehyde (CAS 1000340-13-5)
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- Methyl (2E,4E)-4-(benzenesulfonyl)-5-[(4-methoxyphenyl)amino]penta-2,4-dienoate (CAS 339276-70-9)
- (R)-2-(3-chloro-5-methylphenyl)-2-(methylamino)ethan-1-ol (CAS 1336436-32-8)
- Methyl octahydro-1H-isoindole-5-carboxylate (CAS 1895245-26-7)
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