1-Phenyl-3-pyrrolidinone CAS 128120-02-5
| CAS No. | 128120-02-5 |
| Molecular Formula | C10H11NO |
| Molecular Weight | 161.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-Phenyl-3-pyrrolidinone (C10H11NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1-Phenyl-3-pyrrolidinone (CAS 128120-02-5) is a high-purity analytical reference standard with the molecular formula C10H11NO and a molecular weight of 161.20 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11NO |
| Molecular Weight | 161.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 1 |
Related Phenyl Standards
- 2-Pyrrolidinone,5-methyl-4-(2-methylpropyl)-,(4S,5S)-rel- (CAS 850080-17-0)
- 2-PYRROLIDINONE, 4-(3-METHYLPHENYL) (CAS 1019650-80-6)
- 1-benzyl-3-pyrrolidinone (CAS 775-16-6)
- 2-PYRROLIDINONE, 4-(2-METHYLPHENYL) (CAS 654633-87-1)
- 3-Ethyl-2-pyrrolidinone (CAS 930-92-7)
- L-2-Pyrrolidinone-3,3,4,4,5-d5-5-carboxylic Acid (CAS 1086136-22-2)
- DL-2-Pyrrolidinone-3,3,4,4,5-d5-5-carboxylic Acid (CAS 352431-30-2)
- 2-PYRROLIDINONE, 4-(2-METHOXYPHENYL) (CAS 1020718-50-6)
Recommended Standards
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- 2-(Isopropylamino)isonicotinonitrile (CAS 127680-78-8)
- 5-Methyl-3,4-dihydroisoquinolin-1(2H)-one (CAS 129075-56-5)
- Methyl (2S,4S)-4-hydroxypiperidine-2-carboxylate (CAS 1103929-08-3)
- N-Methyl-5-phenyl-4,5-dihydroisoxazole-3-carboxamide (CAS 918945-67-2)
- 2-Bromo-1-(2,4-dimethoxyphenyl)propan-1-one (CAS 117844-88-9)
- 2-Nitro-4,6-bis(trifluoromethyl)aniline (CAS 320-21-8)
- 2-Methyl-N-(2-methylbenzyl)butan-2-amine (CAS 932267-68-0)
- 2-Amino-3-chloro-5-(trifluoromethoxy)benzoic acid (CAS 433938-46-6)
- N-(2,3,4,9-Tetrahydro-1H-carbazol-3-yl)acetamide (CAS 60480-69-5)
- 1-Hydroxy-4-methylcyclohexane-1-carboxylic acid (CAS 41248-15-1)
- (3-Chloro-4-fluorobenzyl)(4-chlorophenyl)sulfane (CAS 1443347-38-3)
- Acetyl tetrapeptide-9(Dermican LS 9837) (CAS 928006-50-2)
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