2-Chloro-4-(3,4,5-trimethoxyphenyl)nicotinonitrile CAS 1281804-21-4
| CAS No. | 1281804-21-4 |
| Molecular Formula | C15H13ClN2O3 |
| Molecular Weight | 304.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-4-(3,4,5-trimethoxyphenyl)nicotinonitrile.
2-Chloro-4-(3,4,5-trimethoxyphenyl)nicotinonitrile (CAS 1281804-21-4), molecular formula C15H13ClN2O3 and molecular weight 304.73 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-Chloro-4-(3,4,5-trimethoxyphenyl)nicotinonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 304.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-4-(3,4,5-trimethoxyphenyl)nicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H13ClN2O3 |
| Molecular Weight | 304.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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- Methyl 3-chloro-5-[4-(methoxycarbonyl)phenyl]benzoate (CAS 1820685-78-6)
- 2-Chloro-1-(5-(furan-2-yl)-3-(2-(furan-2-yl)vinyl)-4,5-dihydro-1h-pyrazol-1-yl)ethan-1-one (CAS 877964-07-3)
Recommended Standards
- Ethyl 7-(4-chlorophenyl)-4,7-dihydro[1,2,4]-triazolo[1,5-a]pyrimidine-6-carboxylate (CAS 1306738-76-0)
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- 2-amino-N-(2H-1,3-benzodioxol-5-ylmethyl)-6-chlorobenzamide (CAS 1411540-92-5)
- 4-Amino-2-chloro-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzamide (CAS 1018247-50-1)
- 1,3-Propanediamine-N,N,N',N'-tetraacetic Acid (CAS 1939-36-2)
- 1-(3-Bromopropyl)piperidin-4-ol (CAS 113385-30-1)
- N-(2,6-Dimethylphenyl)-N-(2-oxotetrahydrofuran-3-yl)but-3-enamide (CAS 75660-92-3)
- Methyl 4-(2-((3-ethyl-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamido)benzoate (CAS 618879-63-3)
- 5-Bromoquinoline-3-carbonitrile (CAS 1974296-18-8)
- 6-Methyl-2h-chromene-3-sulfonyl chloride (CAS 1235440-49-9)
- N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-(2,4-dichlorobenzoyl)-1H-pyrrole-2-carbohydrazide (CAS 338403-48-8)
- (4E)-4-[(2H-1,3-Benzodioxol-5-yl)methylidene]-2-(2,6-dimethylmorpholin-4-yl)-4,5-dihydro-1H-imidazol-5-one (CAS 866142-91-8)
- Benzyl N-[(S)-1-Benzyl-2-(tosyloxy)ethyl]carbamate (CAS 194935-55-2)
- (β-Asp5)-Delta-Sleep Inducing Peptide (CAS 82602-88-8)
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