1'-Benzyl-6-chloro-7-fluoro-1H-spiro[furo[3,4-c]pyridine-3,4'-piperidin]-1-one CAS 1283090-74-3
| CAS No. | 1283090-74-3 |
| Molecular Formula | C18H16ClFN2O2 |
| Molecular Weight | 346.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1'-Benzyl-6-chloro-7-fluoro-1H-spiro[furo[3,4-c]pyridine-3,4'-piperidin]-1-one (C18H16ClFN2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
1'-Benzyl-6-chloro-7-fluoro-1H-spiro[furo[3,4-c]pyridine-3,4'-piperidin]-1-one (CAS 1283090-74-3) is a high-purity analytical reference standard with the molecular formula C18H16ClFN2O2 and a molecular weight of 346.78 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1'-Benzyl-6-chloro-7-fluoro-1H-spiro[furo[3,4-c]pyridine-3,4'-piperidin]-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H16ClFN2O2 |
| Molecular Weight | 346.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- Ethyl 3-(2-aminoethyl)-1h-indole-5-carboxylate (CAS 7272-54-0)
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- 2-{3-[(2-chlorophenyl)methyl]-2,4,5-trioxoimidazolidin-1-yl}acetamide (CAS 320422-98-8)
- 959578-19-9 Ethyl 5-bromo-1-(4-methylphenyl)-1H-pyrazole-4-carboxylate DTXSID40377228 (CAS 959578-19-9)
- 6-Chlorothiazolo[4,5-b]pyridine-2-thiol (CAS 488742-54-7)
- (R)-1-Cyclobutylethanamine (CAS 778575-09-0)
- Cyclolinopeptide B (CAS 193139-41-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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