1-(2-(Trifluoromethyl)benzyl)pyrrolidin-3-ol CAS 1284019-08-4
| CAS No. | 1284019-08-4 |
| Molecular Formula | C12H14F3NO |
| Molecular Weight | 245.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-(Trifluoromethyl)benzyl)pyrrolidin-3-ol.
1-(2-(Trifluoromethyl)benzyl)pyrrolidin-3-ol (CAS 1284019-08-4) is a high-purity analytical reference standard with the molecular formula C12H14F3NO and a molecular weight of 245.24 g/mol.
The molecular framework of 1-(2-(Trifluoromethyl)benzyl)pyrrolidin-3-ol (C12H14F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(2-(Trifluoromethyl)benzyl)pyrrolidin-3-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H14F3NO |
| Molecular Weight | 245.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 1-{[4-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-ol (CAS 1044769-56-3)
- 1-[4-(Trifluoromethyl)pyridin-2-yl]-1,4-diazepane (CAS 1048921-30-7)
- 4-(3-(Trifluoromethyl)phenyl)tetrahydro-2h-pyran-4-amine (CAS 1094283-09-6)
- 2-methyl-6-[3-(trifluoromethyl)phenyl]morpholine (CAS 1094657-85-8)
- 5-Methyl-2-[3-(trifluoromethyl)phenyl]morpholine (CAS 1099679-67-0)
- 3-((4-(Trifluoromethyl)benzyl)oxy)pyrrolidine (CAS 1121634-73-8)
- n-(1-(4-(Trifluoromethyl)phenyl)ethyl)propionamide (CAS 1197490-33-7)
- 1-Benzyl-3-(trifluoromethyl)pyrrolidin-3-ol (CAS 1211580-89-0)
Recommended Standards
- N-(4-(trifluoromethoxy)benzyl)cyclobutanamine (CAS 1275544-72-3)
- (1-(5-(Trifluoromethyl)pyridin-2-yl)pyrrolidin-2-yl)methanamine (CAS 1285496-63-0)
- 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidin-3-amine (CAS 1271707-10-8)
- 1-[3-(Trifluoromethyl)pyridin-2-yl]piperidin-3-amine (CAS 1305860-95-0)
- (4-Fluoro-3-(methylsulfonamido)phenyl)boronic acid (CAS 1009303-57-4)
- Ethyl 2-(cyclopropanecarbonyl)-3,3,3-trifluoropropanoate (CAS 1502216-04-7)
- 2,2,5,5-Tetramethylimidazolidin-4-one (CAS 16256-42-1)
- 1-(4,6-Dimethyl-1,3-benzothiazol-2-yl)piperidine-3-carboxylic acid (CAS 1119451-38-5)
- 4-(Isobutylamino)-2-(methylthio)pyrimidine-5-carboxylicacid (CAS 1015856-38-8)
- Upadacitinib Impurity 174 (CAS CATO-C4X-2405174)
- 2,3-Difluoro-6-methylbenzonitrile (CAS 1807183-03-4)
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- Eosinophilotactic Peptide (CAS 61756-28-3)
Why CATO?
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