2-(1-Amino-2-(4-fluorophenoxy)ethylidene)malononitrile CAS 1284228-23-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(1-Amino-2-(4-fluorophenoxy)ethylidene)malononitrile.

2-(1-Amino-2-(4-fluorophenoxy)ethylidene)malononitrile (CAS 1284228-23-4) is a high-purity analytical reference standard with the molecular formula C11H8FN3O and a molecular weight of 217.20 g/mol.

Based on its molecular formula C11H8FN3O, 2-(1-Amino-2-(4-fluorophenoxy)ethylidene)malononitrile contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 217.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(1-Amino-2-(4-fluorophenoxy)ethylidene)malononitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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